CHEN, SONG

Release date:2016-05-13  Release:

 


 




CHEN, SONG

Associate Professor of Microbiology and Biochemical Pharmacy

School of Life Science and Technology

Phone: 86-25-83271367

Email: chens@cpu.edu.cn

Research Summary

Dr.CHEN’s research focuses on Biological DrugResearch and Developmentand the Molecular Biology of Aging. He presided overprojects of the National Natural Science Foundation, theNatural Science Foundation of Jiangsu Province, theSpecialized Research Fund for the Doctoral Program of HigherEducation and the Fundamental Research Fundsfor the Central Universities.



Education

2012       Ph.D., Microbiology and Biochemical Pharmacy, China Pharmaceutical University

2009       M.S.,  Microbiology and Biochemical Pharmacy, China Pharmaceutical University

2006       B.S.,   BiotechnologyChina Pharmaceutical University

Academic Experience

2015-      Associate Professor of Microbiology and Biochemical PharmacySchool of Life Science and Technology

2012-2015  Lecturer of Microbiology and Biochemical PharmacySchool of Life Science and Technology

Awards and Honors

2012       Second Prize, Eli Lilly Asia Outstanding Graduate Thesis Award

Publications

  1. Chen S, Yin L, Xu Z, An FM, Liu AR, Wang Y, Yao WB, Gao XD. Inhibiting receptor for advanced glycation end product (AGE) and oxidative stress involved in the protective effect mediated by glucagon-like peptide-1 receptor on AGE induced neuronal apoptosis. Neurosci Lett. 2016;612:193-8.

  2. An FM , Chen S (Co-first author), Xu Z, Yin L, Wang Y, Liu AR, Yao WB and Gao XD. Glucagon-like peptide-1 regulates mitochondrial biogenesis and tau phosphorylation against advanced glycation end product-induced neuronal insult: studies in vivo and in vitro. Neuroscience. 2015;300:75-84.

  3. Chen S, An FM, Yin L, Liu AR, Yin DK, Yao WB, Gao XD. Glucagon-like peptide-1 protects hippocampal neurons against advanced glycation end product-induced tau hyperphosphorylation. Neuroscience. 2014;256:137-46.

  4. Chen S, Ding R, Zhou Y, Zhang X, Zhu R, Gao XD. Immunomodulatory effects of polysaccharide from marine fungus Phoma herbarum YS4108 on T cells and dendritic cells. Mediators Inflamm. 2014;2014:738631.

  5. Liu A, Chen S (Co-first author), Cai S, Dong L, Liu L, Yang Y, Guo F, Lu X, He H, Chen Q, Hu S, Qiu H. Wnt5a through noncanonical Wnt/JNK or Wnt/PKC signaling contributes to the differentiation of mesenchymal stem cells into type II alveolar epithelial cells in vitro. PLoS One. 2014;9(3):e90229.

  6. Zhou Y, Chen S (Co-first author), Ding R, Yao W, Gao X. Inflammatory modulation effect of glycopeptide from Ganoderma capense (Lloyd) Teng. Mediators Inflamm. 2014;2014:691285.

  7. Ma GF, Chen S (Co-first author), Yin L, Gao XD, Yao WB. Exendin-4 ameliorates oxidized-LDL-induced inhibition of macrophage migration in vitro via the NF-κB pathway. Acta Pharmacol Sin. 2014;35(2):195-202.

  8. Chen S, Liu AR, An FM, Yao WB, Gao XD. Amelioration of neurodegenerative changes in cellular and rat models of diabetes-related Alzheimer's disease by exendin-4. Age (Dordr). 2012;34(5):1211-24.

  9. Chen S, Yin DK, Yao WB, Wang YD, Zhang YR, Gao XD. Macrophage receptors of polysaccharide isolated from a marine filamentous fungus Phoma herbarum YS4108. Acta Pharmacol Sin. 2009;30(7):1008-14.

  10. Cai SX, Liu AR, Chen S, He HL, Chen QH, Xu JY, Pan C, Yang Y, Guo FM, Huang YZ, Liu L, Qiu HB. Activation of Wnt/β-catenin signalling promotes mesenchymal stem cells to repair injured alveolar epithelium induced by lipopolysaccharide in mice. Stem Cell Res Ther. 2015;6(1):65.

  11. Yin D, Yin J, Yang Y, Chen S, Gao X. Renoprotection of Danshen Injection on streptozotocin-induced diabetic rats, associated with tubular function and structure. J Ethnopharmacol. 2014;151(1):667-74.

  12. Liu AR, Liu L, Chen S, Yang Y, Zhao HJ, Liu L, Guo FM, Lu XM, Qiu HB. Activation of canonical wnt pathway promotes differentiation of mouse bone marrow-derived MSCs into type II alveolar epithelial cells, confers resistance to oxidative stress, and promotes their migration to injured lung tissue in vitro. J Cell Physiol. 2013;228(6):1270-83.

  13. Yin D, Yao W, Chen S, Hu R, Gao X. Salidroside, the main active compound of Rhodiola plants, inhibits high glucose-induced mesangial cell proliferation. Planta Med. 2009;75(11):1191-5.