Release date:2016-05-17  Release:



Professor of Pharmaceutical Analysis

School of Science

Phone: 86-25-86185150

Email: yanzhengyujiang@hotmail.com

Research Summary

Prof. Yans research interests include instrumental analysis and pharmaceutical analysis. She presided over the completion of subproject of national 863 plan major project, and participated in the completion of many projects of national natural and science foundation of China.  She also presided over more than twenty quality standards of new drug development. Prof. Yans research focus on three aspects: 1. synthesis, characterization and application of new nanomaterials; 2. Monitoring of the environmental water pollution; 3. Development of the drug quality standards.  Prof. Yan has published more than 90 high quality papers and 2 patent applications. She is appointed as reviewer expert of National food and Drug Administration health food, National Science and Technology Awards,National 863 plan, Ministry of education, Jiangsu provincial food and drug administration new drug and health food, Jiangsu Provincial Natural science research project and Hebei Provincial Science and technology.  She is also member of the academic committee of China Medicine University.


2004 Ph.D., Pharmaceutical Analysis, China Pharmaceutical University

2000 M.S., Pharmaceutical Analysis, China Pharmaceutical University

1982 B.S., Chemistry, Wuhan University

Academic Experience

2003-Professor of Pharmaceutical Analysis, Department of Analytical Chemistry, China Pharmaceutical University

1994-2002 Associate Professor of Pharmaceutical Analysis, Department of Analytical Chemistry, China Pharmaceutical University

1988-1993  Lecturer of Pharmaceutical Analysis, Department of Analytical Chemistry, China Pharmaceutical University

1982-1988  Lecturer of Physical Chemistry, Hubei University of Science and Technology

Awards and Honors

2016Outstanding Individual, China Pharmaceutical University,

2015Third Prize, for Jiangsu Challenge Cup, Jiangsu Provincial Education Department

2014First Prize, Guobang Teaching Excellence Award

2014Jiangsu Province 12th Five-Year Higher Education key Teaching Materials

2011Excellent Course of Instrumental Analysisfor Continuing education, Jiangsu Provincial Education Department

2010Tainhuang national prominent teacher for continuing education, The Chinese Adult Education Association

2008First Prize, Excellent Course of Analytical Chemistry, Jiangsu Provincial Education Department

More than 20 Teaching Awards from Jiangsu Provincial Education Department and China Pharmaceutical University



  1. 严拯宇.分析化学实验与指导[M]. 中国医药科技出版社,2005-08(第一版)

  2. 严拯宇.分析化学实验与指导[M]. 中国医药科技出版社,2009-08(第二版)

  3. 严拯宇.分析化学实验与指导[M]. 中国医药科技出版社,2015-09(第三版)

  4. 严拯宇.主编.薄层色谱分析技术在中药分析中的应用[M].北京,中国医药科技出版社,2009-12

  5. 严拯宇.主编.仪器分析[M].南京,东南大学出版社,2009-12(第二版)

  6. 严拯宇,研究生入学考试分析化学学习指导与试题解答[M].南京,东南大学出版社,2009-08(第一版)

  7. 严拯宇,研究生入学考试分析化学学习指导与试题解答[M].南京,东南大学出版社,2010-10(第二版)

  8. 严拯宇. 分析化学[M]. 南京,东南大学出版社,2005-09(第一版)

  9. 严拯宇. 分析化学[M]. 南京,东南大学出版社,2015-04(第二版)

  10. 严拯宇.副主编.药学实用仪器分析[M].北京,高等教育出版社,2006-01

  11. 严拯宇.副主编.分析化学实验[M].北京,科学出版社, 2004-09(第一版)

  12. 严拯宇.主编.分析化学实验[M].北京,科学出版社, 2014-6(第二版)

  13. 严拯宇.副主编.分析化学(上册).科学出版社。2015-6(第四版)


  1. 一种蒸馏器(新型实用专利)Zl20082 214455.3 国家知识产权局 2009

  2. 蒸馏器(外观设计专利)ZL20093 00272010国家知识产权局  2010

Papers (Last three years)

  1. Zhengyu Yan, Zhengwei Zhang, Jianqiu Chen,Biomass-based carbon dots: Synthesis and applicationin imatinib determination[J]Sensors and Actuators B: Chemical 2016,225:469-473.

  2. Zhengyu Yan, Zhengwei Zhang, Yan Yu, Zhen Liu, Jianqiu Chen.Chemiluminescence determination of potassium bromate in flour basedon flow injection analysis[J]Food Chemistry 2016. 190 20–24.

  3. Su YL, Du QQ, Qu XC, et al. Fluorescent yeast containing intracellularly biosynthesized CdSe QDs as a sensitive probe for simple determination of Copper (II) in water and plasma[J]. RSC Advances, 2016, 6(34): 28187-28193.

  4. Zhengyu Yan, Xincheng Qu, Qianqian Niu, Chunqing Tian, Chuanjian Fan, Baofen Ye. A green synthesis of high fluorescence nitrogen-doped graphene quantum dots for the highly sensitive and selective detection of mercury (II) ions and biothiols[J]. Analytical Methods, 2016,8, 1565-1571.

  5. Wei Li, Jun Wang, Zheng-Yu Yan. Development of a sensitive and rapid method for rifampicin impurity analysis using supercritical fluid chromatography [J]. Journal of Pharmaceutical and Biomedical Analysis,2015, 114(10 ) : 341–347.

  6. Zhengyu Yan, Yan Yu and Jianqiu Chen* Glycine-functionalized 1 carbon quantum dots as chemiluminescence sensitization for detection ofm-phenylenediamine AnalyticalMethods 2015,7,1133-1139.

  7. Liao S H, Huang Y, Zuo J X, Yan Z Y. The interaction of CuInS2/ZnS/TGA quantum dots with tyrosine kinase inhibitor and its application[J]. Luminescence, 2015,30: 362-370.

  8. Zhengyu Yan, Zhengwei Zhang, Yan Yu and Jianqiu Chen. Study on the fluorescence resonance energytransfer between CdS quantum dots andEosin Y, [J]. Luminiscence,2015.30:155-158.

  9. ZhengyuYan, JuanShu, YanYu, ZhengweiZhang, ZhenLiu.andJianqiuChen. Preparation of carbon quantum dots based on starch and the spectral properties,[J]. Luminiscence 2015,30:388-392.

  10. Liao S H, Huang Y, Zuo J X, Yan Z Y. The interaction of CuInS2/ZnS/TGA quantum dots with tyrosine kinase inhibitor and its application[J]. Luminescence, 2015,30: 362-370.

  11. Yu Huang, Ying Zhang, Zhengyu Yan* and Shenghua Liao*The assay of ceftazidime and cefepime based on fluorescent quenching of carbon quantum dots[J]. Luminescence, 2015,30(7).

  12. Chen J, An X, Zhang Z, et al. The synthesis and modification of CdTe/CdS core shell quantum dots[J]. Spectrochimica Acta Part A Molecular & Biomolecular Spectroscopy, 2015, 151:506-509.

  13. Wu Sheng-Mei,Su Yilong,Liang Ranran,et al. Crucial factors in biosynthesis of fluorescent CdSe quantum dots in Saccharomyces cerevisiae[J]. Rsc Advances, 2015, 5(96): 79184-79191.

  14. Yan Z Y, Wang L L, Fei M Y, et al. Construction of photodynamic-effect immunofluorescence probes by a complex of quantum dots, immunoglobulin G and chlorin e6 and their application in HepG2 cell killing[J]. Luminescence, 2015.

  15. Yan Z Y, Ai X X, Su Y L, et al. Intracellular Biosynthesis of Fluorescent CdSe Quantum Dots in Bacillus subtilis: A Strategy to Construct Signaling Bacterial Probes for Visually Detecting Interaction Between Bacillus subtilis and Staphylococcus aureus.[J]. Microscopy & Microanalysis the Official Journal of Microscopy Society of America Microbeam Analysis Society Microscopical Society of Canada, 2015.

  16. Sun L, Jiao H, Gao B, et al. Hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry method for the simultaneous determination of l-Valine, l-Leucine, l-Isoleucine, l-Phenylalanine, and l-Tyrosine in human serum[J]. Journal of Separation Science, 2015, 5(5):40-6.

  17. Zhengyu Yan, Jiao Chen, An Xiao ,et al. Effects of representative quantum dots on microorganisms and phytoplankton: a comparative study[J]. Rsc Advances,2015.5,106406–106412.

  18. Zhang Z, Duan Y, Yu Y, et al. Carbon quantum dots: synthesis, characterization, and assessment of cytocompatibility.[J]. Journal of Materials Science Materials in Medicine, 2015, 26(7):1-7.

  19. Zi Lili, Huang Y, Yan ZY, et al. Thioglycolic acid-capped CuInS2/ZnS quantum dots as fluorescent probe for cobalt ion detection[J]. Journal of Luminiscence, 2014(148) :359-363.

  20. Sheng-Mei Wu, Xiao-Juan Sun,Li-Li Wang,Meng-Ying Fei,Zheng-Yu Yan.Singlet oxygen-generating from fluorescence probes based on denatured bovine serum albumin-conjugated CdTe quantum dots and photosensitizer Chlorin e6[J]. J Nanopart Res 2014,16(11):1-9 16:2701.

  21. YAN Zhengyu, XIAO An,LU Hua, LIU Zhen, CHEN Jian qiu* Determination of metronidazole by a flow injectionchemiluminescence method using ZnO doped carbon quantum dots[J].New Carbon Materials,2014329217-220.

  22. YAN Zhengyu,ZHAO Na,LIU Zhen,LU Hua,CHEN Jianqiu. Biomass-Based Carbon DotsSynthesis and Application in Oxytetracyline Hydrochloride Determination[J].CHINESE JOURNAL OF INORGANIC CHEMISTRY ,2014,30(4):937-944.

  23. Zhen Liu, Yan Cui, Jianqiu Chen*, Zhengyu Yan,*The control of bromate formation in ozonation ofbromide-containing water[J].Desalination and Water Treatment,2014(52) 4942–4946.

  24. Zhengyu YanYanYuJianqiu Chen.An Examination of the Interaction of Carbon Quantum Dots with Bovine Serum Albumin by Ultraviolet-Visible and Fluorescence Spectrophotometer[J].Advanced Science Focus,2014(2)92-95.

  25. Shenghua Liao,  Yu Huang,  Ying Zhang, Xiaohui Shan, Zhengyu  Yan, Weiyang Shen .Highly Enhanced Photoluminescence of  AgInS2/ZnS Quantum Dots by Hot-injection Method[J]Materials Research Express 20152.

  26. YAN Z, QIAN J, GU Y, et al. Green biosynthesis of biocompatible CdSe quantum dots in living Escherichia coli cells [J]. Materials Research Express, 2014, 1(1): 015401.

  27. The production and properties of carbon dots.An Xiao, Hua Lv, Zhen Liu, Jianqiu Chen, Zhengyu Yan.Material science. 11(4), 2014 [155-167].  

  28. Huning Jia, Xiaomei Cao, Cong Fu, Jianping Wang, Zhiyao Chen, Bingjie Zou,LiJin, Zhengyu Yan, and Guohua Zhou. Colorimetric Detection of DNA Sequences Using an Organic Solvent to Induce the Aggregation of Label-Free Gold Nanoparticles[J]. Journal of Nanoscience and Nanotechnology. 2013 Vol. 13, 3805–3809.

  29. Chengui Li, Xiaomei Wang, Chao Ye, Yunqing Wang,Yuzhu Hu, and Zhengyu Yan. Synthesis and Characterization of Fluorescence Resonance Energy Transfer-Based Nanoprobes by Coating CdTe QDs with Rhodamine B in Gelatin Nanoparticles. Journal of Nanoscience and Nanotechnology,Vol. 13, 4330–4333, 2013.

  30. Sheng-Mei.Wu, Jing.Chen, Xiao-Xia.Ai, Zheng-Yu.Yan. Detection of Escherichia coli in drugs with antibody conjugated quantum dots as immunofluorescence probes [J] .J Pharm Biomed Anal. (2013) 9– 13.

  31. Lu H ,Shan XH, Chen J ,et al. Preparation of carbon quantum dots in wood charcoal and their interaction with bovine serum albumin NEW CARBON MATERIALS2013,28(4): 307-312.

  32. Chao Gao, Zhen Liu , Jianqiu Chenand Zhengyu Yan∗∗. A novel uorescent assay for oxytetracycline hydrochloride based on uorescence quenching of water-soluble CdTe nanocrystals[J]. Luminescence.2013,28(3):378-383.