ZHONG, WENYING

Release date:2016-05-17  Release:


ZHONG, WENYING

Professor of Pharmaceutical Analysis

Dean of School of Science

Phone: 86-25-86185180

Email: wenyingzhongnj@163.com


Research Summary

Professor Zhongs research interests focus on developing new materials and methods for pharmaceutical analysis, which includes:

1. Development of nanoparticle-based drug delivery system;

2. Fabrication of nanomaterials for bioanlaysis;

3. Synthesis of quantum dots and its biomedical application.


Education

2000~2004 Ph.D. in Physical Chemistry, Nanjing University

1987~1990   M.S. in Analytical Chemistry, Nanjing University

1983~1987B.S. in Analytical Chemistry, Nanjing University


Academic Experience

1993-presentChinaPharmaceuticalUniversity, Instructor , Associate Professor; Professor

    1. Hebei Medical University, Instructor


Awards and Honors

2011Second prize, Jiangsu Teaching Achievement Award

2010 Excellent dissertation advisor to master’s candidate in Jiangsu Province, Department of Education of Jiangsu Province

2009  Foundation of Top-level Talents on Six Fields in Jiangsu Province, Department of Personnel of jiangsu Province

2009  the first state-level prize of "Outstanding Achievements in Education", Education Ministry of China

2004“Qing Lan” program fortalentedyoung teachers of Jiangsu Province, Department of Education of Jiangsu Province


Publications

  1. Chang Shu, Bin Huang, Xiangdong Chen, Yan Wang, Xuequan Li, Li Ding, Wenying Zhong*.Facile synthesis and characterization of water soluble ZnSe/ZnS quantum dots for cellar imaging. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2013(104)143-149. (IF1.977)

  2. Chang ShuRuixin LiJin GuoLi DingWenying Zhong*. New generation of β-cyclodextrin-chitosan nanoparticles encapsulated quantum dots loaded with anticancer drug for tumor-target drug delivery and imaging of cancer cells. J Nanopart Res (2013) 15:1927. ( IF 2.175)

  3. Lili Pang,Jian Xu,Chang Shu,Jin Guo,Xiaona Ma,Yu Liu and Wenying Zhong*. Characterization and cancer cell targeted imaging properties of human antivascular endothelial growth factor monoclonal antibody conjugated CdTe/ZnS quantum dots.2014.3.21..Luminescence. 2014,29,1177-1182. (IF1.518)

  4. Xiaona Ma, Chang Shu, Jing Guo, Lili Pang, Lin Su, Degang Fu, Wenying Zhong*. Targeted cancer therapy based on single-wall carbon nanohorns with Doxorubicin in-vitro and in-vivo. Journal of nanoparticle research.2016,16,7 (IF2.184)

  5. Chang Shu, Ruixin Li, Yajun Yin, Deyan Yin, Yueqing Gu, Li Ding*, and Wenying Zhong*. Synergistic Dual-Targeting Hydrogel Improves Targeting and Anticancer Effect of Taxol in Vitro and in Vivo, Chem. Commun. 2014, 50:15423-15426. (IF=6.718)

  6. Chang Shu, Li Ding *, Wenying Zhong * Fluorescence resonance energy transfer between ZnSe ZnS quantum dots and bovine serum albumin in bioaffinity assays of anticancer drugs  Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy . 2014,131,195-202. (IF=2.353)

  7. Nannan Li, Qian Zhao, Chang Shu, Xiaona Ma, Ruixin Li, Hongjun Shen, Wenying Zhong*. Targeted killing of cancer cells in vivo and in vitro with IGF-IR antibody-directed carbon nanohorns based drug delivery [J]. International Journal of Pharmaceutics, 2015, 478 (2):644-654. (IF=3.7)

  8. Qian Zhao, Nannan Li, Chang Shu, Ruixin Li, Xuequan Li, Ran Wang, Wenying Zhong*. Docetaxel loaded Single-wall Carbon Nanohorns using anti-VEGF antibody as a targeting agent: characterization, in vitro and in vivo antitumor activity [J]. Journal of nanoparticle research , 2015,17,5(IF=2.184)

  9. Ruixin Li, Chang Shu, Wei Wang, Xiaoliang, Wang, Hui Li, Danke Xu, Wenying Zhong*. Encapsulation of 10-hydroxy camptothecin in supramolecular hydrogel as an injectable drug delivery system, Journal of Pharmaceutical Science , 2015.104(7):2266-2275. (IF=3.007)

  10. Ying Zhou, Hongjing Cui, Chang Shu, Ya Ling,Ran Wang, Hongmei Li, Yadong Chen, Tao Lu and Wenying Zhong*, A SupramolecularHydrogel Based on Carbamazepine ,Chemical Communications,2015,51,15294-15296. (IF=6.834)

  11. Hongjing Cui,Ranwang,Ying Zhou,Chang Shu, Fengjuan Song and Wenying Zhong*, Dual-function fluorescent probe for cancerimaging and therapyLuminescence2016,31(3),813-820.IF=1.518

  12. Junling Wang.XiaonaMa .Chang Shu.Nannan Li.Qian Zhao.Ran Wang.Wenying Zhong*.Pharmacokinetic and biodistribution studies of doxorubicinloaded single-wall carbon nanohorns in mice, Journalof nanoparticle research 2015,17:384. (IF=2.184)

  13. Ya Ling,  Yuan Gao,  Chang Shu,a Ying Zhou,Wenying Zhong* and   Bing Xu Using a peptide segment to covalently conjugate doxorubicin and taxol for the study of drug combination effectRSC Adv., 2015,5, 101475-101479. ( IF:3.8)

  14. Xia Wei, Hui Li, Zhonghui Li, Maika Vuki, Yu Fan, Wenying Zhong*, Danke Xu. Metal-enhanced fluorescent probes based on silver nanoparticles and its application in IgE detection .[J] Analytical and Bioanaltical Chemistry. 2012,402(3),1057-1063

  15. Wenying Zhong* ,Cui Zhang, Qin Gao, Hui Li, Highly sensitive detection of lead(II) ion using multicolor CdTe quantum dotsMicrochimica acta2012,176(2),101-107.

  16. Zhong Wenying*, Huang Bin, Study on the CdTe/CdS-Rhodamine B FRET queching method for determination of lead(Ⅱ) and the interaction mechanism [J]Chinese Journal of Analysis Laboratory, 2011,30(11):37-42

  17. Zhong Wenying*, Huang Bin, Chen Lin, Shu Chang. Fluorescence resonance energy transfer quenching for determination of vitamin B_2Journal of China Pharmaceutical University 2011,42(6):527-533.

  18. Hui Li, Ziyin Sun, Wenying Zhong, Nao Hao, Danke Xu, Hong-Yuan Chen. Ultrasensitive Electrochemical Detection For DNA Arrays Based on Silver Nanoparticle Aggregates, Anal.Chem., 2010, 82,5477-5483.

  19. LI Hui, Wenying Zhong*, XU Dan- ke. Preparation of Silver Nanoparticles as Bio-Tag and its Applications in the Biological Analysis, Guangzhou Chemical Industry,2010,38(7):3-6.

  20. XU Guo- Feng, LI Hui, ZHANG Cui, SUN Zi- Yin, Wenying Zhong*, XU Dan-Ke, CHEN Hong-Yuan. Research and Application of Visual Detection Based on Quantum Dots Coupled with Silver Enhancement, Chinese JAnalChem, 2010,38(10): 1383-1387.

  21. Qing Chen, Qiongming Liu, Zhoumin Li, Wenying Zhong, Wei He, Danke Xu. A visual chip-based coimmunoprecipitation technique for analysis of protein–protein interactions, Analytical Biochemistry, 2010,404, 244–246.

  22. WANG Ying, LI ZhongHui, Wenying Zhong, LI Hui, XU DanKe. CHEN HongYuan. Rhodamine B doped silica nanoparticle labels for protein microarray detection. SCIENCE CHINA CHEMISTRY .2010, 53(4),747-751.

  23. LI Hui, Wenying Zhong*, XU Dan-Ke. Preparation of Biotinylated Silver Nanoparticles and Its Application of Visual Detection Method for Protein Chip, Chem. J. Chinese Universities,2010, 11, 2184-2189.

  24. Wenying Zhong*, LI Zhou-Min, XU Dan-ke. Visual detection method for microplate protein arrays, Chinese Journal of Analysis Laboratory, 2010, 29(5):5-8.

  25. CHEN Jian-qiu, LIANG Jia-ran, Wenying Zhong, JI Rong. Study on the interaction of hesperidin and four metal-hesperidin coordination compounds with bovine serum albumin, Chinese Journal of Analysis Laboratory, 2010, 29(1):14-17.

  26. Wenying Zhong*, ZHANG Cui, XU Guo-feng, YAN Ming, XU Dan-ke. Study on the estrogen derivative marked by CdTe quantum dots, Spectroscopy and Spectral Analysis, 2011, 31(8), 2215-2219.

  27. Liang JiaRan, Wenying Zhong*, YU Jun Sheng. Rapid Aqueous Synthesis of High quality CdTe Colloidal Quantum Dots, Chem. J. Chinese Universities, 2009, 30(1), 14-18.

  28. Wenying Zhong*, Jiaran Liang, Junsheng Yu. Systematic study of the interaction of cobalt ions with different-sized CdTe quantum dots, Spectrochimica Acta Part A, 2009, 74(3), 603-606.

  29. Lu Xia, Wenying Zhong*, YU Jun-sheng. Synthesis and characterization of high quantum yield CdTe quantum dots in aqueous phase, Chinese Journal of Analysis Laboratory, 2009, 28(1):36-40.

  30. Liang Jiaran, Wenying Zhong*, Yu Junsheng. Application of Quantum Dots( QDs) as Fluoresent Probes in Quantitative Analysis, PROGRESS IN CHEMISTRY, 2008, 20(9): 1385-1390.

  31. Xia Ling, Wenying Zhong*, Qi Huang, Kunyi Ni. Spectroscopic Studies on the Interaction of Pazufloxacin with Calf Thymus DNA, J. Photochem. And Photobiology B: Biology: 2008, 93(3): 172–176.

  32. Xia Ling, Dawei Deng, Wenying Zhong*, Junsheng Yu. Quantitative determination of pazufloxacin using water-soluble quantum dots as fluorescent probes, Spectroscopy and Spectral Analysis, 2008, 28(6): 1317.

  33. YUAN Hong-kun, LU Xia, Wenying Zhong*. Preparation of liriope muscari baily saponins C solid lipid nanoparticles, Pharm Care & Res, 2007, 7(6): 413-416.

  34. XU Na, Wenying Zhong*, ZHU Dan-ni. Solid Lipid Nanoparticles for Enhancing the Bioavailability of Poorly Soluble Drugs, CHINESEARCHIVESOFTRADITIONALCHINESEMEDICINE, 2007, 25(8): 1605-1607.

  35. Wenying Zhong, Yuchun Wang, JunSheng Yu, Yingqiu Liang, Kunyi Ni. The Interaction of Human Serum Albumin with a Novel Antidiabetic Agent- SU-118, J. Pharm. Sci., 2004, 93(4): 1039-1046.

  36. Wenying Zhong, JunSheng Yu, Yingqiu Liang, Keqiang Fan, Luhua Lai. Chlorobenzylidine―Calf Thymus DNA interaction (Ⅱ): Circular Dichroism and Nuclear Magnetic Resonance studies, Spectrochimica Acta Part A, 2004, 60(13): 2985-2992.