CHEN, JIAQUAN

Release date:2016-05-17  Release:

 


CHEN, JIAQUAN

Associate Professor of Analytical Chemistry


School of Science

Phone: 86-25-86185150

Email: brunochen@cpu.edu.cn

  

Research Summary

Associate Professor CHEN’s research focuses on the enantioseparation of chiral drugs by capillary electrophoresis (CE). Chiral separation has remained animportant task in pharmaceutical analysis because each enantiomer of a drug often behaves differently during pharmacokinetic and pharmacodynamic processes in the human body.Therefore, analytical methods of high efficiency and selectivity are required for both safety and industrial monitoring of theenantiomericpurity of chiral drugs. CEis a powerful chiral separation technique owing to itsmajor advantages, including high efficiency, low consumptionof reagent, and flexibility of separation modes.



Education

2004       M.S., Analytical ChemistryNorthwest University

2001       B.S., Applied Chemistry, Anhui Normal University

Academic Experience

2004-      Associate Professor of Analytical Chemistry, Department of Analytical Chemistry, China Pharmaceutical

University

Publications

(1) Rong Yin#, Jiaquan Chen#, Yonggang Zhao, Xiaobin Jia, Zhiyuan Zhang, Linag Feng, Hui Wang, Jingjing Wang, Fenxia Zhu*. Simultaneous determination of six alkaloid components in rat plasma and its application to pharmacokinetic study of Danmu preparations by an ultra fast liquid chromatography-electrospray ionization-tandem mass spectrometry, J Chromatogr B, 2015, 983-984: 10-17.

(2) Jiaquan Chen, Yingxiang Du*, Fenxia Zhu, Bin Chen, Qi Zhang, Shuaijing Du, Ping Li. Study of the enantioseparation capability of chiral dual system based on chondroitin sulfate C in CE, Electrophoresis, 2015, 36(4): 607-614.

(3)Jiaquan Chen, Yingxiang Du*, Fenxia Zhu, Bin Chen. Evaluation of the enantioselectivity of glycogen-based dual chiral selector systems towards basic drugs in capillary electrophoresis, J Chromatogr A, 2010, 1217(45): 7158-7163.

(4) Jiaquan Chen, Yingxiang Du*, Fenxia Zhu, Bin Chen. Glycogen: A novel branched polysaccharide chiral selector in CE, Electrophoresis, 2010, 31(6): 1044-1050.