WANG, YUE

Release date:2016-05-17  Release:

WANG, YUE

Associate Professor of Chemistry

School of Sciences

Phone: 86-25-86185163

Email: zwy_1115@126.com

Research Summary

Professor WANG’s research focuses on the

  1. Nano chemistry including:

Preparation series of nanovehicels as the potential drug-delivery carrier and their bioactivity evaluation at both cellular and animal levels; Discovery of the novel metal complexes nanomedicine based on the specific assembly; Synthesis of functional nanomaterial for target diagnosis and treatment via radionuclide label and molecular imaging

(2) Medicinal Chemistry including:

Design and synthesis of the potential small drug molecules as potent CDKs inhibitors

Education

2006  Ph.D., Medicinal Chemistry, Osaka Pharmaceutical University, Japan

2000  M.S., Applied Chemistry, University of Science and Technology of China

1997  B.S., Chemistry, Anhui Normal University, China

Academic Experience

2015-2016  Visiting Scholar in University of Michigan, USA

2011-2014Post-doctor in Nanjing University, China

2004-2005  Visiting Scholar in Kinki University, Japan

Awards and Honors

2014   Fusun Scholar, Shanghai Fusun Pharmaceutical Group

2012Qing Lan Project, Academic Leader, Jiangsu Province

2006   Qing Lan Project, Outstanding Young Teacher, Jiangsu Province

Publications

Books:

  1. Inorganic Chemistry, Zhejiang University Press2014.8


Papers and Articles(recent 5 years):

  1. Guowu Lin, Yue Wang*, Qingfa Zhou, Weifang Tang, Jian Wang and Tao Lu*, A facile synthesis of 1-substituted β carboline derivatives via MINISCI-REACTIONSynthetic Communications, 2011, 41, 3541-3550.

  2. Yue Wang, Qingfa Zhou, Guowu Lin, Lili Di and Tao Lu*, Synthesis and Crystal Structure of 4-Oxo-1,2,4-triazino[4,5-a]benzimidazole, Chinese Journal of Structure  Chemistry, 2011, 30, 97-100.

  3. Guowu Lin, Yue Wang*, Qiaomei Jin, Taotao Yang, Jiemei Song, Yi Lu, Qingjie Huan, Ke Song, K, Jun Zhou and Tao Lu*, Synthesis, structures and the biological activity study on the metal complexes of 2-(4-aminophenyl) benzothiazole derivative, Inorganica Chimica Acta, 2012, 382, 35-42.

  4. Guowu Lin, Yue Wang*, Qingfa Zhou, Jian Wang, Taotao Yang, Zhanwei Wang and Tao Lu*, Synthesis of a novel series of 1,6 disubstituted-3-(cyclohexylmethoxy)-b carboline derivatitives via MINISCI REACTION, Synthetic Communications, 2012, 42, 1895–1910.

  5. Yue Wang, Qiaomei Jin, Guowu Lin, Taotao Yang, Zhanwei Wang, Yi Lu, Yimin Tang, Lifang Liu* and Tao Lu*, Synthesis and Structure of the β-Carboline Derivatives and Their Binding Intensity with Cyclin-Dependent Kinase 2, Chemical & Pharmaceutical Bulletin, 2012, 60 435–441.


  1. Yi Lu, Ting Ran, Guowu Lin, Qiaomei Jin, Jianling Jin, Hongmei Li, Hao Guo, Tao Lu*, and Yue Wang*, Novel 1H-Pyrazole-3-carboxamide Derivatives: Synthesis, Anticancer Evaluation and Identification of Their DNA-Binding Interaction Evaluation and Identification of Their DNA-Binding Interaction, Chemical & Pharmaceutical Bulletin, 2014, 62238-246

  2. Qiao-Mei Jin, Yi Lu, Jian-Lin Jin, Hao Guo, Guo-Wu Lin, Yue Wang*, Tao Lu*, Synthesis, Characterization, DNA Binding Ability and Cytotoxicity of the Novel Platinum(II), Copper(II), Cobalt(II) and Nickel(II) Complexes with 3-(1H-benzo[d]imidazol-2-yl)- β-Carboline, Inorganica Chimica Acta, 2014, 421,91-99

  3. Hongmei Li, Zhen Li, Jin Zhao, Baoqiang Tang, Yanhong Chen, Yikun Hu, Zhengda He and Yue Wang*Carboxymethyl chitosan-folic acid-conjugated Fe3O4@SiO2 as a safe and targeting antitumor nanovehicle in vitroNanoscale Research Letter, 2014, 9146-156.

  4. Yuanhang Zhou, Yue Wang*, Xiulei Zhang, Jiajuan Peng, Hongmei Li, Zhen Li, Preparation and Characterization of Photosensitive and Magnetic Targeting Graphene Oxide Nanocomposite,Journal of Nanoscience and Nanotechnology, 2015, 15, 2009-2014.

  5. Yue Wang, Chi Zhang, Hongmei Li, Guoxing Zhu, Song-Song Bao, Shiqiang Wei, Li-Min Zheng, Min Ren and Zheng Xu*, Synthesis, characterization and in vitro anticancer activity of the biomolecule-based coordination complex nanotubes,Journal of Material Chemistry B, 2015, 3, 296-305.

  6. Hongmei Li, Zhen Li, Lixiang Liu, Tao Lu* and Yue Wang*An efficient goad nanocarrier for combined Chemophotodynamic therapy on tumor cellsRSC Advances2015, 5, 34831-34848

  7. Zhen Li,Hongmei Li, Lixiang Liu, Xinyi You, Chaofeng Zhang* and Yue Wang*A pH-sensitive nanocarrier for co-delivery of doxorubicin and camptothecin to enhance chemotherapeutic efficacy and overcome multidrug resistance in vitro multidrug resistance in vitro, RSC Advances2015, 5, 77097-77105