CHEN, ZHEN

Release date:2016-05-17  Release:

CHEN, ZHEN

Professor of Pharmacology

Director of The Pharmaceutical animal experimental center Deputy DirectorofLab Center of Pharmacy & Medicine

School of Pharmacy

Phone: 86-025-83271181

Email: czcpu@163.com

Research Summary

Professor CHEN’s research focuses onBiochemical and pharmacological studies on liver and metabolic diseases. She has undertaken or participated in variousprojects of national, provincial and ministerial level. She recently published a paper as the first author in PNAS, aninternational journal, which has great effect on the study of pathological mechanism and intervention measures of inflammation related diseases, such as coronary atherosclerosis, metabolic syndrome and tumor.  

Education

2005      Ph.D., Pharmacology, China Pharmaceutical University

1986      B.S., PharmacologyShanghai Medical University

Academic Experience

2011-     Professor of Pharmacology, School of Pharmacy

Awards and Honors

1993      Third Prizefor Science and technology progress of the State Education Commission

Undertaking or participating in variousprojects of national, provincial and ministerial level

Publications

Books

1JI Hui, CHEN Zhen, et al.Pharmacology.Publishing House of Southeast University (First Edition).

2QIAN Zhiyu, CHEN Zhen, et al. Experiment and Guide for Pharmacology.China Medical Science and Technology Press (Third Edition).

Papers and Articles

1Xianjing Li, Duowei Wang, Zhen Chen, et al. Gαi1 and Gαi3 regulate macrophage polarization by forming a complex containing CD14 and Gab1. PNAS, 2015, 112(15): 4731-4736.

2Yong Yang, Xian-Jing Li, Zhen Chen, et al.Wogonin Induced Calreticulin/Annexin A1 Exposure Dictates the Immunogenicity of Cancer Cells in a PERK/AKT Dependent Manner. Plos One, 2012, 7(12): e50811.

3Rong Fu, Zhen Chen, et al. XJP-1, a novel ACEI, with anti-inflammatory properties in HUVECs. Atherosclerosis, 2011(219): 40–48.

4JL TIAN, X KE, Z CHEN, et al. Melittin liposomes surface modified with poloxamer 188: in vitro characterization and in vivo evaluation. Pharmazie, 2011(66): 362–367.

5Li Zhao, Zhen Chen, et al. Developmental toxicity and genotoxicity studies of wogonin. Regulatory Toxicology and Pharmacology, 2011(60): 212–217.

6Li Zhao, Zhen Chen, et al. Synergistic effect of 5-fluorouracil and the flavanoid oroxylin A on HepG2 human hepatocellular carcinoma and on H22 transplanted mice. Cancer Chemother Pharmacol, 2010, 65(3): 481-489.

7X PANG, Z CHEN, et al.Potential of a Novel Polysaccharide Preparation (GLPP) from Anhui-Grown Ganoderma lucidum in Tumor Treatment and Immunostimulation. JOURNAL OF FOOD SCIENCE, 2007, 72(6).