DING, YA​

Release date:2016-05-17  Release:

 

DING, YA

Distinguished Research Fellow of Pharmaceutical Analysis

School of Pharmacy

Phone: 86-25-83271326

Email: dingya@cpu.edu.cn

Research Summary

Dr. Dings research focuses on the research and application of biomaterials in the nanoscale, especially (1) the system structure control on the treatment efficacy and biological toxicity of drug-related nanovehicles, and (2) the quality control of nanomaterials in biomedicine.


Education

2007       Ph.D., Analytical Chemistry, Nanjing University

2004       M.S., Medicinal ChemistryChina Pharmaceutical University

1999       B.S., Pharmaceutical ChemistryChina Pharmaceutical University

Academic Experience

2016-Distinguished Research Fellow of Pharmaceutical Analysis, China Pharmaceutical University

2010-2015Associate Professor of Pharmaceutical Analysis, China Pharmaceutical University

2013-2014Visiting scholar of Chemistry, University of Massachusetts-Amherst

2008-2012Postdoctoralof Biology, Nanjing University

2007-2010Lecturer of Pharmaceutical Analysis, China Pharmaceutical University

1999-2000Research Intern, Jiangsu Provincial Institute of Materia Medica

Awards and Honors

2012Higher Sciences Outstanding Achievement Award , Ministry of Education

2010       New Century Excellent Talents, Ministry of Education

2010       Outstanding young teachers training object, Qing Lan Project

Publications

1.Yu-Feng Chen, Jin Hong (co-first author), Dong-Yan Wu, Ying-Ying Zhou, Mathew D’Ortenzio, Ya Ding*, Xing-Hua Xia, In vivo mapping and assay of matrix metalloproteases for the liver tumor diagnosis. RSC Advances 2016, 6, 8336-8345. DOI: 10.1039/C5RA26172D. (SCI IF=3.84)

2.Ning Zhang, Huan Chen (co-first author), Ai-Yun Liu, Jia-Jia Shen, Vishva Shah, Can Zhang, Jin Hong, Ya Ding*, Gold conjugate-based liposomes with hybrid Cluster Bomb structure for liver cancer therapy. Biomaterials 2016, 74, 280-291. DOI: 10.1016/j.biomaterials.2015.10.004 (SCI IF=8.557)

3.Fang Yan, Miaomiao Sun, Taijun Hang*, Jing Sun, Xia Zhou, Xin Deng, Liang Ge, Hai Qian, Ding Ya, Wenlong Huang, A rapid and sensitive UPLC–MS/MS method for determination of HZ08in rat plasma and tissues: Application to a pharmacokinetic study ofliposome injections. Journal of Pharmaceutical and Biomedical Analysis 2015, 102, 246–252. (SCI IF=2.979)

4.Fen-Fen Zhang, Yu-Qin Zhao, Jian-Ping Fan, Li-Gang Liu, Rui-Wen Li, Wen-Bin Shen*, Ya Ding*, Structural identification of 4-benzyl-voglibose hydrochloride monohydrate via NMR and single-crystal X-ray diffraction methods. Carbohydrate Research 2015, 402, 81-86. (SCI IF=1.929)

5.Fen-Fen Zhang, Meng-Hong Jiang, Lin-Lin Sun, Feng Zheng, Lei Dong, Vishva Shah, Wen-Bin Shen*, Ya Ding*, Quantitative analysis of Sitagliptin using 19F-NMR method: A universal technique for fluorinated compounds detection. Analyst 2015, 140, 280–286. (SCI IF 4.107)

6.Juan-Juan Liang, Ying-Ying Zhou (co-first author), Jun Wu, Ya Ding*, Gold nanoparticle-based drug delivery platform for antineoplastic chemotherapy. Current Drug Metabolism 2014, 15, 620-631. (SCI IF=3.487) DOI: 10.2174/1389200215666140605131427

7.Quan-Ying Bao, Ning Zhang, Dong-Dong Geng, Jing-Wei Xue, Mackenzie Merritt, Can Zhang, Ya Ding*, The enhanced longevity and liver targetability of Paclitaxel by hybrid liposomes encapsulating Paclitaxel-conjugated gold nanoparticles. International Journal of Pharmaceutics 2014, 477, 408-415. (SCI IF 3.785) DOI: 10.1016/j.ijpharm.2014.10.040

8.Ya Ding, Ziwen Jiang (co-first author), Krishnendu Saha, Chang Soo Kim, Sung Tae Kim, Ryan F. Landis, Vince Rotello*, Gold nanoparticles for nucleic acid delivery. Molecular Therapy 2014, 22, 1075–1083. (SCI IF=6.425) DOI: 10.1038/mt.2014.30

9.Ya Ding, Juan-Juan Liang, Zhao-Yu Liu, Di Wu, Lei Dong, Xing-Hua Xia*, Wen-Bin Shen, Can Zhang*, Development of a liver-targeting gold-PEG-galactose nanoparticle platform and the structure-function study. Particle & Particle Systems Characterization 2014, 31, 347-356 (SCI IF=0.537) DOI: 10.1002/ppsc.201300120

10.Xiang Jin, Ran Mo, Ya Ding*, Wei Zheng, Can Zhang*, Paclitaxel-loaded N-octyl-O-sulfate chitosan micelles for superior cancer therapeutic efficacy and overcoming drug resistance. Molecular Pharmaceutics 2014, 11, 145−157 (SCI IF=4.787) DOI: 10.1021/mp400340k

11.Mo Chen, Yuan Zhang, Xiao-Ting Que, Ya Ding*, Lin Yang, Ai-Dong Wen, Tai-Jun Hang*, Pharmacokinetic study of inosiplex tablets in healthy Chinese volunteers by hyphenated HPLC and tandem MS techniques. Journal of Pharmaceutical Analysis 2013, 3, 387–393.

12.Ya Ding*, Ying-Ying Zhou, Huan Chen, Dong-Dong Geng, Dong-Yan Wu, Jin Hong, Wen-Bin Shen, Tai-Jun Hang, Can Zhang, The performance of thiol-terminated PEG-paclitaxel-conjugated gold nanoparticles. Biomaterials 2013, 34, 10217–10227. (SCI IF 8.312) DOI: 10.1016/j.biomaterials.2013.09.008

13.Quan-Ying Bao, Dong-Dong Geng, Jing-Wei Xue, Geng Zhou, Shen-Yang Gu, Ya Ding*, Can Zhang*, Glutathione-mediated drug release from Tiopronin-conjugated gold nanoparticles for acute liver injury therapy. International Journal of Pharmaceutics 2013, 446, 112-118. (SCI IF=3.789) DOI: 10.1016/j.ijpharm.2013.01.073

14.Ya Ding, Peng Zhang, Xiao-Yan Tang, Can Zhang*, Song Ding, Hai Ye, Qi-Long Ding, Wen-Bin Shen, Qi-Neng Ping, PEG prodrug of gambogic acid: Amino acid and dipeptide spacer effects. Polymer 2012, 53, 1694-1702. (SCI IF=3.766)

15.Ya Ding, Bo Jin, Gang Gu, Xing-Hua Xia*, One-Step Pyrolysis Method for the Synthesis of Highly Efficient 3D Hollow Carbon Nanostructures Supported Catalysts. Journal of Materials Chemistry 2009, 19, 1941-1946. (SCI IF=5.968) DOI: 10.1039/b913767j

16.Ya Ding, Yu-Lin Hu, Gang Gu, Xing-Hua Xia*, Controllable Synthesis and Formation Mechanism Investigation of Prussian Blue Nanocrystals by Using Polysaccharide Hydrolysis Method. Journal of Physical Chemistry C 2009, 113, 14838–14843. (SCI IF=4.835) DOI: 10.1021/jp905704c

17.Ya Ding, Gang Gu, Xing-Hua Xia*, Cysteine-Grafted Chitosan Mediated Gold Fabrication: From Nanochains to Microcubes. Journal of Materials Chemistry 2009, 19, 795-799. (SCI IF=5.968) DOI: 10.1039/b816886e

18.Ya Ding, Gang Gu, Hui-Lin Yang, Xing-Hua Xia*, Photosynthesis of 1D Prussian blue Nanowires by using DNA Templates. Journal of Nanoscience and Nanotechnology 2009, 9, 2381-2386. (SCI IF=1.149) DOI: 10.1166/jnn.2009.SE18

19.Ya Ding, Xing-Hua Xia*, Preparation and characterization of hollow carbon nanospheres supported metallic catalysts by using one-step pyrolysis method. Journal of Nanoscience and Nanotechnology 2008, 8, 1512-1517. (SCI IF=1.93)

20.Ya Ding, Gang Gu, Xing-Hua Xia*, Electrochemical Deposition and Mechanism Investigation of Prussian blue on Graphic Carbon Paste Electrode from an acidic Ferricyanide Solution. Journal of Solid State Electrochemistry 2008, 12, 553-558. (SCI IF=1.597) DOI: 10.1007/s10008-007-0342-0

21.Dai Zhang, Ya Ding, Wei Gao, Hong-Yuan Chen, Xing-Hua Xia*, Synthesis of Ordered Macroporous Pt/Ru Nanocomposites for the Electrooxidation of Methanol. Journal of Nanoscience and Nanotechnology 2008, 8, 979-985. (SCI IF=1.93)

22.Can Zhang, Yao Cheng, Guowei Qu, Xiaoli Wu, Ya Ding, Zhihong Cheng, Liangli Yu, Qineng Ping*, Preparation and characterization of galactosylated chitosan coated BSA microspheres containing 5-fluorouracil. Carbohydrate Polymers 2008, 72, 390–397. (SCI IF=2.64)

23.Ya Ding, Xing-Hua Xia*, He-Sheng Zhai*, Reversible assembly and disassembly of gold nanoparticles directed by a zwitterionic polymer. Chemistry-A European Journal 2007, 13, 4197-4302. (SCI IF=5.454)

24.Can Zhang, Ya Ding, Liang-Li Yu, Qi-Neng Ping*, Polymeric micelle systems of hydroxycamptothecin based on amphiphilic N-alkyl-N-trimethyl chitosan derivatives. Colloids and Surfaces B: Biointerfaces 2007, 55, 192–199. (SCI IF=2.593)

25.Ya Ding, Xing-Hua Xia*, Can Zhang, Synthesis of metallic nanoparticles protected with N, N, N-trimethyl chitosan chloride via a relatively weak affinity. Nanotechnology 2006, 17, 4156-4162. (SCI IF=3.446)

26.Ya Ding, Xing-Hua Xia*, Facile synthesis of hollow carbon nanospheres from hollow chitosan nanospheres. Journal of Nanoscience and Nanotechnology 2006, 6, 1101-1106. (SCI IF=1.929)

27.Can Zhang, Ya Ding, Qi-Neng Ping, Liang-Li Yu*, Novel chitosan-derived nanomaterials and their micelle-forming properties. Journal of Agricultural and Food Chemistry 2006, 54, 8409-8416. (SCI IF=2.562)

28.Can Zhang, Ya Ding, Qi-Neng Ping*, Preparation and characterization of novel N-alkyl-N-trimethyl chitosan derivatives. Polymer Materials Science and Engineering (in Chinese) 2006, 22, 200-203. (IE)

29.Yan-Li Yao, Ya Ding, Le-Sheng Ye, Xing-Hua Xia*, Two-step pyrolysis process to synthesize highly dispersed Pt-Ru/carbon nanotube catalysts for methanol electrooxidation. Carbon 2006, 44, 61-66. (SCI IF=4.373)

30.Can Zhang, Qi-Neng Ping*, Ya Ding, Synthesis and characterization of chitosan derivatives carrying galactose residues. Journal of Applied Polymer Science 2005, 97, 2161-2167. (SCI IF=1.187)

31.Can Zhang, Qi-Neng Ping, Ya Ding, Yao Cheng, Jian Shen*, Synthesis, characterization, and microsphere formation of galactosylated chitosan. Journal of Applied Polymer Science 2004, 91, 659-665. (SCI IF=1.187)

32.Ya Ding, Can Zhang, Wei-Yi Hua*, Diels-Alder 反应在不对称合成中的研究进展(Recent advance of the Diels-Alder reaction in asymmetric synthesis). Chinese Journal of Organic Chemistry (in Chinese) 2003, 23, 1076-1084. (Review) (SCI IF=0.662)