DING, ZHENHUA

Release date:2016-05-17  Release:

DING, ZHENHUA

Associate Professor of Medicinal Chemistry

School of Pharmacy

Phone: 86-25-8618XXXX

Email: zhding@cpu.edu.cn

Research Summary

Our research interests focus on the development of new chemical transformations and their applications to the construction of novel target molecules. Research directions include: creation of more efficient catalysts to achieve effective and sustainable synthesis of molecules of medical importance; design of new and convenient strategies for the synthesis of drug intermediates; development of chemical methods and approaches which can be easily used in industry to generate economic benefits to the society.


Education

2013       Ph.D., Organic Chemistry, Nanyang Technological University

2009       M.S., Organic Chemistry, Soochow University

2006       B.S., Chemistry, Soochow University

Academic Experience

2014-      Associate Professor of Medicinal Chemistry, China Pharmaceutical University

2013-2014 Research Fellow of Biological ChemistryNanyang Technological University

Awards and Honors

2013       Chinese Government Award for Outstanding Self-financed Students Abroad, Chinese Scholarship Council

Publications

1. Zhenhua Ding, Naohiko Yoshikai*. Cobalt-Catalyzed Intramolecular Olefin Hydroarylation Leading to Dihydropyrroloindoles and Tetrahydropyridoindoles. Angew. Chem. Int. Ed.2013, 52, 8574-8578.

2. Zhenhua Ding, Naohiko Yoshikai*. Mild and Efficient C2-Alkenylation of Indoles with Alkynes Catalyzed by a Cobalt Complex. Angew. Chem. Int. Ed.2012, 51, 4698-4701.

3. Zhenhua Ding, Naohiko Yoshikai*. C2-Alkylation of N-Pyrimidyl Indole with Vinylsilane via Cobalt-Catalyzed C–H Bond Activation. Beilstein J. Org. Chem. 2012, 8, 1536-1542.

4. Zhenhua Ding, Naohiko Yoshikai*. Cobalt-Catalyzed Alkenylation of Thiazoles with Alkynes via C–H Bond Functionalization. Synthesis2011, 2561-2566.

5. Zhenhua Ding, Naohiko Yoshikai*. Cobalt-Catalyzed Addition of Azoles to Alkynes. Org. Lett. 2010, 12, 4180-4183.

6. Zhenhua Ding, Jin Yang, Ting Wang, Zongxuan Shen and Yawen Zhang*. Dynamic kinetic resolution of beta-keto sulfones via asymmetric transfer hydrogenation. Chem. Commun. 2009, 571-573.

7. Zhiyuan Chen, Beili Lu, Zhenhua Ding, Ke Gao, Naohiko Yoshikai*. α-Palladation of Imines as Entry to Dehydrogenative Heck Reaction: Aerobic Oxidative Cyclization of N-Allylimines to Pyrroles. Org. Lett. 2013, 15, 1966-1969.