​LI, JUAN

Release date:2016-05-17  Release:


 

Li, Juan

Professor of Pharmaceutical Preparations

School of Pharmacy

Phone: 86-025-83171287

Email: lijuan9958@cpu.edu.cn

Research Summary

Professor Li’s research focuses on the synthesis of novel targeting materials, construction of polymeric conjugates and tumor targeting drug delivery system. Her research directions are development of novel pharmaceutical polymers and targeting drug delivery system, evaluation of controlled drug release system and pharmacokinetics.She is rated ashigh-level personnel ofsix talents peak, and served as evaluation expert for National Science and Technology Progress Award, Center for Drug Evaluation, and Technology Project of Jiangsu Province. Professor Li is also reviewer of numerous journals at home and abroad. She has hostedand participated inmany research projects, such as the National Natural Science Foundation Projects, 11th and 12th Five-Year Plan.

Education

2007       Ph.D., Pharmaceutics, China Pharmaceutical University

1984      B.S.,   Pharmaceutical preparationsChina Pharmaceutical University

Academic Experience

2011-      Professor of Pharmaceutics, China PharmaceuticalUniversity

2000-2011 Associate Professor of Pharmaceutics, China Pharmaceutical University

Awards and Honors

2015       Poster presentation of “Mechanism of a novel redox-responsive paclitaxel conjugate for efficacy intracellular drug release and cancer therapy”, Chinese Pharmaceutical Conference

2015       Poster presentation of “Targeting exosomal miRNA with pH-sensitive liposome coated chitosan-siRNA nanoparticles for inhibition of hepatocellular carcinoma metastasis”, International Nano Controlled Release Conference

2014      Second Prize for Graduate Forum of “Construction and anti-tumor mechanism of novel polymeric micelles for targeted intracellular drug delivery based on hyaluronic acid and GSH-response”Chinese Pharmaceutical Conference

2000-     Science Technology Achievement Award and Teaching Achievement Award, China Pharmaceutical University

Publications

[1] Shaoping Yin, Jue Huai, Xi Chen, Yong Yang, Xinxin Zhang, Yong Gan, Guangji Wangd,Xiaochen Gu, Juan Li*. Intracellular delivery and antitumor effects of a redox-responsive polymeric paclitaxel conjugate based on hyaluronic acid.Acta Biomaterialia. 2015,26:274-285. [IF: 6.025]

[2] Na Wu, Xinxin Zhang, FeiFei Li, Tao Zhang, Yong Gan*, Juan Li*. Spray-dried powders enhance vaginal siRNA delivery by potentially modulating the mucus molecular sieve structure. International Journal of Nanomedicine. 2015,10:5383-5396. [IF: 4.383]

[3] Xinxin Zhang#, Feifei Li#, Shiyan Guo, Xi Chen, Xiaoli Wang, Juan Li*, Yong Gan*. Biofunctionalized polymer-lipid supported mesoporous silica nanoparticles for release of chemotherapeutics in multidrug resistant cancer cells. Biomaterials. 2014,35: 3650-3665. [IF: 8.312]

[4] HongzhiQiao#, Juan Li#*, Yang Wang, Qineng Ping, Guangji Wang, XiaochenGu. Synthesis and Characterization of Multi-Functional Linear-Dendritic Block Copolymer for Intracellular Delivery of Antitumor Drugs. International Journal of Pharmaceutics. 2013,452:363-373. [IF: 3.785]

[5] Yanlei Zhao#, Juan Li#*, Hua Yu, Guangji Wang*.Synthesis and characterization of a novel polydepsipeptide contained tri-block copolymer (mPEG-PLLA-PMMD) as self-assembly micelle delivery system for paclitaxel. International journal of Pharmaceutics. 2012,430:282-291.[IF: 3.458]

[6] Lingqiang Xu#, Hua Yu#,Shaoping Yin, Ruixia Zhang, Yudan Zhou, Juan Li*. Liposome-based delivery systems for ginsenoside Rh2:in vitro and in vivo comparisons. Journal of Nanoparticle Research.2015,17:415-428. [IF: 2.184]

[7] Shaoping Yin, Juan Li*, Nannan Li, Guangji Wang, Xiaochen Gu. Preparation and characterization of long-circulating PELMD/mPEG–PLGA-mixed micelles for 10-hydroxycamptothecin. Journal of Nanoparticle Research. 2014,16:2274-2288. [IF: 2.278]

[8] Juan Li*, Hua Yu, Shuai Li , Guangji Wang. Enhanced distribution and extended elimination of glycyrrhetinic acid in mice liver by mPEG-PLA modified (mPEGylated) liposome. Journal of Pharmaceutical and Biomedical Analysis. 2010,51:1147-1153. [IF: 2.78]