LIU, JIANPING

Release date:2016-05-17  Release:

LIU, JIANPING

Professor of Pharmaceutics

School of Pharmacy

China Pharmaceutical University.

Phone: 86-25-83271293O

Email: jianpingliu1293@163.com

Research Summary

Professor LIU’s research focuses on the biological function drug carrier system, the sustained and controlled release preparations, the transdermal drug delivery system and the new preparation of Chinese traditional Chinese. In recent years shehas been in charge of the National Natural Science Foundation of China, NZ-China Research Alliance Programme, Major  Project  of National  Science  and  Technology  of  China  for  New  Drugs  Development. National Technology R&D Program for the 11th five-year plan, National Technology R&D Program for the 10th five-year plan and Six talent peaks project” of Jiangsu Province

Education

2001.9-2005.7 Ph.D of Pharmaceutics, China Pharmaceutical University.

1978.10-1982.7 Bachelor of Pharmacy, China Pharmaceutical University.

Academic Experience

2003.7 so far:  Professor of Pharmaceutics(Doctoral supervisor),

Department of Pharmaceutics, China Pharmaceutical University.  

1995.7-2003.6:  Vice professor of Pharmaceutics (Master supervisor),

Department of Pharmaceutics, China Pharmaceutical University.

1988.7-1995.6: Lecturer of Pharmaceutics,

Department of Pharmaceutics, China Pharmaceutical University.

1982.7-1988.6: Assistant of Pharmaceutics,

Department of Pharmaceutics, China Pharmaceutical University.  

1999.03-1999.09: Visiting scholar of school of pharmacy in The

University of Otago, New Zealand.


Awards and Honors

2004 Third Prize, for Nanjing science and Technology Progress Award three prize.

awards.

2011 –Forth Prize, for the national population and Family Planning Commission of science and Technology Progress Award first prize.


PublicationsMajor books and papers published in recent years

Books

Liu Jianping (editor)"biopharmaceutics and pharmacokinetics" fifth edition of people's Medical Publishing House, 2016,

Liu Jianping(editor), “biopharmaceutics and pharmacokinetics" fourth edition of people's Medical Publishing House, 2011.

Papers and Articles( * : Correspondence author)

1.Wenli Zhang, Guangji Wang, Esther See, John P. Shaw, Bruce C. Baguley, Jianping Liu*, Satya Amirapu, Zimei Wu *. Post-insertion of poloxamer 188 strengthened liposomal membrane and reduced drug irritancy and in vivo precipitation, superior to PEGylation.J. Control. Release. 2015, 203:161-169.

2.Hongxiang Yan, Jin Li, Zhenghua Li, Wenli Zhang*, Jianping Liu*. Tanshinone IIA-loaded pellets developed for angina chronotherapy: Deconvolution-based formulation design and optimization, pharmacokinetic and pharmacodynamic evaluation. European Journal of Pharmaceutical Sciences. 2015, 76:156-164.

3.Lisha Liu1, Hongliang He1, Mengyuan Zhang, Shuangshuang Zhang, Wenli Zhang, Jianping Liu*. Hyaluronic acid-decorated reconstitude high density lipoprotein targeting atherosclerotic lesion. Biomaterials, 2014, 35(27): 8002–8014.

4.Hongliang He, Lisa Liu, Jianping Liu*, HuiBai, Ji Wang, Mengyuan Zhang, Zimei Wu. Arachidonic Acid-modified Lovastatin Discoidal Reconstituted High Density Lipoprotein Markedly Decrease the Drug Leakage during the Remodeling Behaviors Induced by Lecithin Cholesterol  Acyltransferase. Pharmaceutical Research, 2014, 31(7): 1689-1709.

5.Zhang W, Wang G, Falconer JR, Baguley BC, Shaw JP, Liu J*, Xu H, See E, Sun J, Aa J, Wu Z. Strategies to Maximize Liposomal Drug Loading for a Poorly Water-soluble Anticancer Drug. Pharmaceutical Research. 2014, 1-11.

6.Wenli Zhang, Hongliang He, Jianping Liu*, Ji Wang, Suyang Zhang, Shuangshuang Zhang, Zimei Wu*. Pharmacokinetics and atherosclerotic lesions targeting effects of tanshinone IIA discoidal and spherical biomimetic high density lipoproteins. Biomaterials. 2013, 34(1):306-19.

7.Jin Li, Pan Liu, Jianping Liu*, Wenli Zhang, Jikun Yang, Yongqing Fan. Novel TanshinoneA ternary solid dispersion pellets prepared by a single-step technique: in vitro and in vivo evaluation. European journal of pharmaceutics and biopharmaceutics. 2012, 80:426-432.

8.Junting Jia, Yan Xiao, Jianping Liu*, Wenli Zhang, Hongliang He, Liang Chen, Mengyuan Zhang. Preparation, characterizations, and in vitro metabolic processes of paclitaxel-loaded discoidal recombinant high-density lipoproteins. Journal of Pharmaceutial Sciences. 2012, 101:2900-2908.

9.Wenli Zhang, Jin Li, Jianping Liu*, Ji Wang, Yan Xiao. Tanshinone IIA-loaded reconstituted high density lipoproteins: Atherosclerotic plaque targeting mechanism in foam cell model and pharmacokinetics in rabbits. Pharmazie,2012, 67(4):324-330.

10.Wenli Zhang, Yan Xiao, Jianping Liu*, Zimei Wu, Xiao Gu, Yiming Xu, Hui Lu. Structure and remodeling  behavior  of  drug-loaded  high  density their atherosclerotic plaque targeting mechanism in foam cell model. International journal of pharmaceutics, 2011, 419: 314-321.

11.Zhang WL, Gu X, Hui Bai, Ruhui Yang, Chendong Dong, Jianping Liu*. Nanostructured lipid carriers constituted from high-densiy lipoprotein components for delivery of a lipophilic cardiovascular drug. International journal of pharmaceutics. 2010, 391: 313-321.

12.Wenli Zhang, Jianping Liu*, Suchun Li, Mengyuan Chen, Huan Liu. Preparation and evaluation of stealth Tashinone IIA-loaded solid lipid nanoparticles: Influence of Poloxamer 188 coating on phagocytic uptake. Journal of Microencapsulation, 2008, 25(3): 203-209.

13.Xiao Gu, Wenli Zhang, Jianping Liu*, Zimei Wu. Preparation of Lovastatin-loaded protein-free nanostructured lipid carrier resembling high density lipoprotein and evaluation of its in vitro foam cell targeting behavior. AAPS PharmScitech. DOI: 10.1208/s12249-010-9454-4.

14.Junting Jia, Chendong Dong, Wenli Zhang, Yanxia Cui, Jianping Liu*. Eevaluation of pharmacokinetic and pharmcodynamic relationship for oral sustained-release atenolol pellets in rats. Journal of pharmaceutical and biomedical analysis. 2011,55:342-348.

15.Xiaoyun Zhang, Jianping Liu*, Hua Qiao, Huan Liu, Jingman Ni, Wenli Zhang, Yanbin Shi. Formulation optimization of dihydroartemisinin nanostructured lipid carrier using response surface methodology. Powder Technology. 2010,197 (1-2): 120-128.

16.Yanxia Cui, Zimei Wu, Jianping Liu*, et al. Preparation, Safety, Pharmacokinetics, and    Pharmacodynamics of Liposomes Containing Brucea javanica Oil. AAPS PharmSciTech. 2010, 2010,11(2):878-884.

17.Xiaowen Zhou, Ying Li, Xiaoqun Jiang, Lu Qiu and Jianping Liu*. Release of copper and indomethacin from intrauterine devices immersed in simulated uterine fluidThe European Journal of Contraception and Reproductive Health Care, Month 2010;15:1–8.

18.Xiaoyun Zhang, Jianping Liu*, Hua Qiao, et al., Determination and Pharmacokinetics of Isoliquiritigenin in Rat Plasma by RP–LC After Intravenous Administration, Chromatographia, 2009, 70, 423–430.

19.Yanli Gao , Jinying Liang , Jianping Liu*, et al, Double-layer weekly sustained release transdermal patch containing gestodene and ethinylestradiol International Journal of Pharmaceutics2009, 377:128–134.

20.Huan LiuYing Li, Jian-ping Liu*, Comparison of the Content, Uniformity of Dosage Units and Dissolution Rate of Triphasic Oral Contraceptives from Two Pharmaceutical Factories, Journal of Reproduction & Contraception, 2009, Jun.,20(2):123-129.