LIU, WENYUAN

Release date:2016-05-17  Release:


LIU, WENYUAN

Professor of Pharmaceutical Analysis

Director of Department of Pharmaceutical Analysis

School of Pharmacy

Phone:025-83271038

liuwenyuan@cpu.edu.cn

Research Summary

Research direction is modern instrumental analysis on key problems of drug R&D. Mainly focus on: 1) the discovery or screening of active components in traditional Chinese medicines by modern analytical methods; 2) the quality control and ADME assessment based on modern analytical techniques. Has published more 40 research papers onJournal of Chromatography AJournal of Chromatography BJournal of Pharmaceutical and Biomedical Analysis, etc. Now is leading two research works of National Natural Science Foundation of China (NSFC). Research work has helped to complete preclinical study of three new drugs.

Education

2008   Visiting Scholar, University of California, San Diego (UCSD)  

2004   Ph.D., Pharmaceutical Analysis, China Pharmaceutical University

1996   M.S., Pharmaceutical Analysis, China Pharmaceutical University

1991   B.S., Chemistry, Shaanxi Normal University

Academic Experience

2013-   Director of Department of Pharmaceutical Analysis,ChinaPharmaceutical University

2013-    Professor of Pharmaceutical Analysis, China Pharmaceutical University

2006-2013  Associated Professor of Pharmaceutical Analysis, China Pharmaceutical University

1996-2006  Instructor of Pharmaceutical Analysis, ChinaPharmaceutical University

1991-1993  Teaching Assistant of Organic Chemistry, Shaanxi UniversityofChinese Medicine

Awards and Honors

2015 Jiangsu higher education micro teaching competition Award, Jiangsu Education

2011  Jiangsu higher education teaching achievement award, Jiangsu Education

2007  Jiangsu Science and technology progress prize, for Basic research and development of the application of anti-tumor drugs based on natural products, Jiangsu Provincial People's Government

Publications

1. Desheng Hou, Jingjing Fan, Lingfei Han, Xiaoling Ruan, Feng Feng, Wenyuan Liu*, Feng Zheng*. Determination of small halogenated carboxylic acid residues in drug substances by high performance liquid chromatography-diode array detection following derivatization with nitro-substituted phenylhydrazines. Journal of Chromatography A, 2016, 1355:73-79. (IF 4.25)

2. Menglin Wei, Jiajia Liu,   Yuanyuan Xia,   Feng Feng, Wenyuan Liu*, Feng Zheng. A polydiacetylene-based fluorescence assay for the measurement of membrane affinity. RSC Advances, 2015, 5: 66420- 66425. (IF 3.85)

3. Yuanyuan Shi, Chunyan Hong, Jian Xu, Xiaoling Yang, Ning Xie, Feng Feng*, Wenyuan Liu*.Simultaneous quantification of two canthinone alkaloids of Picrasma quassioides in rat plasma by liquid chromatography-tandem mass spectrometry and its application to a rat pharmacokinetic study. Journal of Chromatography B, 2015, 986-987:100-107. (IF 2.69)

4. Tian Guo, Yuanyuan Shi, Li Zheng, Feng Feng, Feng Zheng*, Wenyuan Liu*. Rapid and simultaneous determination of sulfonate ester genotoxic impurities in drug substance by liquid chromatography coupled to tandem mass spectrometry: comparison of different ionisation modes. Journal of Chromatography A, 2014, 1355:73-79. (IF 4.25)

5. Rui Deng, Yunhui Xu, Feng Feng*, Wenyuan Liu*. Identification of poliumoside metabolites in rat feces by high performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry. Journal of Chromatography B, 2014, 969:285-296. (IF 2.69)



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