TU, JIASHENG

Release date:2016-05-17  Release:


 

JIASHENG TU


Department of Pharmaceutics

China Pharmaceutical University

No. 24 Tong Jia Xiang

Nanjing, 210009

P. R. China

Tel: 0086-25-83271305Fax: 0086-25-83301606

E-Mail: jiashengtu@cpu.edu.cn; jiashengtu@aliyun.com

ResidenceNo. 1-1105 Huilin Greenland, Heilongjiang Road

Nanjing, 210009

P. R. China

Tel: 0086-25-83427660


Education

Jan. 2002-Sep. 2003: Post Doctoral Research Fellow. Major: Pharmaceutical Sciences.   Thomas J. Long School of Pharmacy and Health Sciences, University of the Pacific, Stockton, CA 95211


Sept 1986-June 1992:  Graduate Student. Major:Pharmaceutics. Ph. D awarded in June 1992. China Pharmaceutical University, Nanjing 210009, China


Sept 1981-July 1986: Undergraduate Student. Major: Pharmacy. Bachelor degree awarded in July 1986. Beijing Medical University, Beijing, P.R. China


Employment

October 2003- present: Professor of Pharmaceutics, Department of Pharmaceutics, China Pharmaceutical University, Nanjing 210009, China


Jan 2002-Sept 2003: Post Doctoral Research Fellow in pharmaceutical sciences,Thomas J. Long School of Pharmacy and Health Sciences, University of the Pacific, Stockton, CA 95211


Oct 2000-May 2001: Reviewer, Center of Drug Evaluation (CDE) of State Food and Drug Administration (SFDA), Beijing, China.


July 1992-Oct 2000: Teacher of Pharmaceutics, Department of Pharmaceutics, China Pharmaceutical University, Nanjing 210009, China



Publication

1. Ammar Ouahab, Jiasheng Tu*, et al. Novel pH-sensitive charge-reversal cell penetrating peptide conjugated PEG-PLA micelles for docetaxel delivery: in vitro study, Progress in Pharmaceutical Sciences, 2014, 466(1-2): 233-245.

2. Jifeng Shi, Jiasheng Tu*, et al. Arginine-stabilized mPEG-PDLLA (50/50) polymeric micelles of docetaxel by electrostatic mechanism for tumor-targeted delivery, Drug Delivery, 2015, 22(2): 168-181.

3. Yourui Xu, Jiasheng Tu*, et al. Antitumor activity of TNF-α after intratumoral injection using an in situ thermosensitive hydrogel, Drug Development and Industrial Pharmacy, 2015, 41(3): 369-374.

4. Xiang Ling, Jiasheng Tu*, et al. Tumor-targeting delivery of hyaluronic acid-platinum(IV) nanoconjugate to reduce toxicity and improve survival, Polymer Chemistry, 2015, 6(9): 1541-1552.

5. Chang Li, Jiasheng Tu*, et al. Paclitaxel-loaded cholesterol-conjugated polyoxyethylene sorbitol oleate polymeric micelles for glioblastoma therapy across the blood-brain barrier, Polymer Chemistry, 2015, 6(14): 2740-2751.

6. Yan Shen, Jiasheng Tu*, et al. Co-delivery of siRNA and paclitaxel into cancer cells by hyaluronic acid modified redox-sensitive disulfide-crosslinked PLGA–PEI nanoparticles, RSC Advances, 2015, 5(58): 46464-46479.

7. Chang Li, Jiasheng Tu*, et al. Novel designed polyoxyethylene nonionic surfactant with improved safety and efficiency for anticancer drug delivery, Int J Nanomedicine, 2014, 9: 2089-2100.

8. Ouahab Ammar, Jiasheng Tu*, et al. Development and characterization of stabilized double loaded mPEG-PDLLA micelles for simultaneous delivery of paclitaxel and docetaxel, Drug Development and Industrial Pharmacy, 2014, 7: 860-868.

9. Yourui Xu, Jiasheng Tu*, et al. Synthesis, characterization, biodegradability and biocompatibility of a temperature-sensitive PBLA-PEG-PBLA hydrogel as protein delivery system with low critical gelation concentration, Drug Development and Industrial Pharmacy, 2014, 40(9): 1264-1275.

10. Mezghrani Omar, Jiasheng Tu*, et al. Hepatocellular carcinoma dually-targeted nanoparticles for reduction triggered intracellular delivery of doxorubicin, International Journal of Pharmaceutics, 2015, 478(2): 553-568.

11. Xiaofeng Xu, Jiasheng Tu*, et al. Preparation and in vitro characterization of thermosensitive and mucoadhesive hydrogels for nasal delivery of phenylephrine hydrochloride, Eur J Pharm Biopharm, 2014, 88(3): 998-1004.

12. Yerong Xiong, Jiasheng Tu*, et al. A poly(γ, L-glutamic acid)-citric acid based nanoconjugate for cisplatin delivery, Biomaterials, 2012, 33(29): 7182-7193.

  1. Chunmeng Sun, Jiasheng Tu*, et al. Method development and validation for the determination of indiquinoline tartrate, a novel kappa opioid agonist, and its related substances by high-performance liquid chromatography, J Chromatogr Sci, 2012, 50(4): 343-348.

  2. Chunyu Yang, Jiasheng Tu*, et al. Cationic polymer-based micro-emulgel with self-preserving ability for transdermal delivery of diclofenac sodium, Drug Delivery, 2014.

  3. Chang Li, Jiasheng Tu*, et al. Immunosafety and chronic toxicity evaluation of monomethoxypoly(ethylene glycol)-b-poly(lactic acid) polymer micelles for paclitaxel delivery, Drug Delivery, 2014.

  4. Chunmeng Sun, Jiasheng Tu*, et al. Interaction between cell-penetrating peptides and acid-sensitive anionic oligopeptides as a model for the design of targeted drug carriers, Mol Pharm, 2014, 11(5): 1583-1590.

  5. Jiasheng Tu*, et al. Risk assessment of supply chain for pharmaceutical excipients with AHP-fuzzy comprehensive evaluation, Drug Dev Ind Pharm, 2015.

  6. Yan Shen, Jiasheng Tu*, et al. Formulation and evaluation of Cyclosporin A emulgel for ocular delivery, Drug Delivery, 2015.

  7. Yan Shen, Jiasheng Tu*, et al. Enhancing effect of Labrasol on the intestinal absorption of ganciclovir in rats, Drug Dev Ind Pharm, 2011, 37(12): 1415-1421.

  8. Yan Shen, Jiasheng Tu*, et al. Multivesicular liposome formulations for the sustained delivery of ropivacaine hydrochloride: preparation, characterization, and pharmacokinetics, Drug Delivery, 2011, 18(5): 361-366.

  9. Ying Xu, Jiasheng Tu*. Optimization of Ophthalmic Liposome of Ganciclovir by Box-Behnken Design, Latin American Journal of Pharmacy, 2014, 33(2): 251-257.

  10. Yan Shen, Jiasheng Tu*. OCULAR PHARMACOKINETICS AND BIOEQUIVALENCE STUDY OF AZITHROMYCIN IN RABBITS BY LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY (LC-MS/MS) METHOD, Journal of Liquid Chromatography and Related Technologies, 2013, 36(14): 1931-1946.

23. Jiasheng Tu*, et al. Formulation and Pharmacokinetic Studies of Acyclovir Controlled-Release Capsules, Drug Development and Industrial Pharmacy, 2001; 27(7): 687-692.

24. Yan Shen, Jiasheng Tu*,et al. A novel tumor-targeted delivery system with hydrophobized hyaluronic acid-spermine conjugates(HHSCs) for efficient receptor-mediated siRNA delivery,International Journal of Pharmaceutics,2011,414(1-2): 233-243.

25.Yan Shen, Jiasheng Tu*,et al.Rapid, sensitive and selective liquid chromatography–tandem mass spectrometry (LC–MS/MS) method for the quantification of topically applied azithromycin in rabbit conjunctiva tissues, Journal of Pharmaceutical and Biomedical Analysis, 2010,52(1): 99-104.

26.Yerong Xiong, Weiwei Jiang, Jiasheng Tu*,et al, A Poly(γ, l-glutamic acid)-citric acid based nanoconjugate for cisplatin delivery, Biomaterials, 2012,33(29): 7182-7193.

27.Yan Shen, Jiasheng Tu*,et al.Synthesis and characterization of low molecular weight hyaluronic acid-based cationic micelles for efficient siRNA delivery,Carbohydrate Polymers,2009,77(1): 95-104.

28.Jiasheng Tu*, Pengmei Li, et al.HPLC determination of pirenzepine dihydrochloride in rabbit aqueous humor, Journal of Chromatography B, 2005, 822(1-2): 300-303.

29.Jiasheng Tu*, Yan Shen, Preparation and ocular pharmacokinetics of ganciclovir lipsomes,AAPS J.2007:9(3):E371-7.

30.Jiasheng Tu*, Pengmei Li,et al. Ocular Permeability of Pirenzepine Hydrochloride Enhanced by Methoxy poly(ethylene glycol)-poly(D,L-lactide) Block Copolymer, Drug Development and Industrial Pharmacy,2007(33):1-9.

31. Jiasheng Tu*,et al. Alginate microparticle prepared by spray-coagulation method:preparation,drug loading and release characterization,International Journal of Pharmaceutics,2005(10),303,171-181.

32. Jiasheng Tu*,Sam Bolla,et al, Studies on alginate microspheres of methylene blue.Pharmaceutical Biotechnologies,2004,(6):356-360.

33. Jiasheng Tu*, Sha Zhong and Pengmei Li, Studies on Acyclovir-Dextran Conjugate: Synthesis and Pharmacokinetics,Drug Development and Industrial Pharmacy,2004,30(9):959-965.

34. Jiasheng Tu*,et al. Formulation and Pharmacokinetic Studies of Acyclovir Controlled-Release Capsules,Drug Development and Industrial Pharmacy,2001;27 (7): 687-692.