WU, ZHENGHONG

Release date:2016-05-17  Release:


WUZHENGHONG

Professor of Pharmaceutics

School of Pharmacy

Phone: 86-15062208341

Email: zhenghongwu66@cpu.edu.cn

Research Summary

Professor WU’s current research interests include nanoscale-based targeted delivery of drugs, peptides, siRNA in order to enhance the efficiency of treatment; use and characterization of macromolecules for drug delivery; nanoparticle formulation, characterization and testing; modified-release preparations; preclinical in vitro and in vivo biopharmaceutical evaluation of drugs; intracellular fate and molecular mechanisms of action of drugs.

Education

2003, Ph.D., Pharmaceutics, China Pharmaceutical University

1997, M.S., Pharmaceutical analysis, China Pharmaceutical University

1990, B.S., Pharmacy, Fudan University (former Shanghai Medical University)

Academic Experience

2014-    Professor of pharmaceutics, China Pharmaceutical University

2014-2016Professor of pharmaceutics, Xinjiang Medical University

2005-2013Associate Professor of pharmaceutics, China Pharmaceutical University

2012-2013  Visiting Scholar of pharmaceutics,Rutgers University

2010-2011Assistant mayor for management of science and technology, Taixing Municipal Government of Jiangsu Province

2003-2005 Postdoctoral Fellow of biology, Academy of Military Medical Science

2003-2004Assistant Professor of pharmaceutics, China Pharmaceutical University

1997-2003Clinical pharmacist-in-chief, the Drum Tower Hospital Affiliated to Nanjing University

1990-1994 Clinical Pharmacist, the First Affiliated Hospital of Anhui Medical University

Awards and Honors

2010 National Elaborate Course approved by the Ministry of Education of the P.R.China, Industrial Pharmaceutics. Gived by Zhou Jianping, Ping Qineng, Wu Zhenghong & Tu Jiasheng.

2011 "Advanced Individual" for cooperation of government, enterprise, school and scientific research institution named by Taixing Municipal Government of Jiangsu Province, P.R.China

Publications(Representative Papers)

  1. Yingchun Jiang, Xuanyu Meng, Zhenghong Wu*, Xiaole Qi*. Modified chitosan thermosensitive hydrogel enables sustained andefficient anti-tumor therapy via intratumoral injection. Carbohydrate Polymers, 2016,144: 245-253.

  2. Xiaole Qi, Jiayi Qin, Yuchao Fan, Xiaoxue Qin, Yujie Jiang, Zhenghong Wu*. Carboxymethyl Chitosan-Modified Polyamidoamine Dendrimer Enables Progressive Drug Targeting of Tumors via pH-Sensitive Charge Inversion, Journal of Biomedical Nanotechnology, 2016, 12: 667-678.  

  3. Xiaole Qi, Xiaoxue Qin, Rong Yang, Jiayi Qin, Wenyan Li, Kun Luan, Zhenghong Wu*, Li Song, Intra-articular Administration of Chitosan Thermosensitive In Situ Hydrogels Combined With Diclofenac Sodiume Loaded Alginate Microspheres, Journal of Pharmaceutical Sciences, 2016, 105: 122-130.

  4. Xiaole Qi, Yao Rui, Yuchao Fan, Haiyan Chen, Ning Ma, Zhenghong Wu*. Galactosylated chitosan-grafted multiwall carbon nanotubes forpH-dependent sustained release and hepatic tumor-targeted deliveryof doxorubicin in vivo. Colloids and Surfaces B: Biointerfaces. 2015, 133: 314-322.

  5. Xiaole Qi, Yuchao Fan, Huan He, Zhenghong Wu*.Hyaluronic acid-grafted polyamidoamine dendrimers enable longcirculation and active tumor targeting simultaneously. Carbohydrate Polymers. 2015,126: 231-239.

  6. Xiaole Qi, Jiayi Qin, Ning Ma, Xiaohua Chou, Zhenghong Wu*.Solid self-microemulsifying dispersible tablets of celastrol: Formulation development, charaterization and bioavailability evaluation.International Journal of Pharmaceutics.2014,472 (1-2): 40-47.

  7. Ziwei Zhang, Xiaole Qi, Xiangbo Li, Jiayu Xing, Xuehua Zhu, Zhenghong Wu*.A novel pulsatile drug delivery system based on the physiochemical reaction between acrylic copolymer and organic acid: In vitro and in vivo evaluation International Journal of Pharmaceutics.2014, 462(1):66-73.

Text Books

  1. Essentials of Pharmaceutical Professional Knowledge (I) for Licensed Pharmacist Examination. China Medical Technology Press, Beijing. 2016 (editor-in-chief)

  2. Pharmaceutics (State licensed pharmacist qualification examination palm-sized series).China Medical Technology Press, Beijing. 2012,2013,2014 (editor-in-chief)

  3. Pharmaceutics. People's Medical Publishing House, Beijing. 2013 (editor)

  4. Nano-pharmaceutics. Jiangsu Phoenix Publishing & Media Corporation Limited, Nanjing. 2011(editor-in-chief)

  5. CD for Licensed Pharmacist Examination Exercises (Traditional Chinese Medicine).Beijing Union Medical Audiovisual Press, Beijing. 2011(editor-in-chief)

  6. CD for Licensed Pharmacist Examination Exercises (Pharmacy).Beijing Union Medical Audiovisual Press, Beijing. 2011(editor-in-chief)

  7. Exam-oriented Workbook for Licensed Pharmacist. Beijing Union Medical University Press, Beijing. 2010, 2011(the first editor)

  8. Industrial Pharmaceutics. China Press of Traditional Chinese Medicine, Beijing. 2010 (subeditor)

Patents

  1. Zhenghong Wu  with co-inventors: Zhu Xuehua, Qi Xiaole, Xing Jiayu, Zhang ZIwei, Meng Xuanyu, Lu Xianfeng, Li Haodong, Xu Xu.Capsule of famotidine floating adhesion type micro tablet and its preparation. CN Patent No. ZL201410004001.3. (March 2, 2016)

  2. Zhenghong Wu with co-inventors: Lu Junjun, Gao Yicai, Wang Bogang, Wang Fang, Tao Qingxian, Zhang Ji. A method for preparing drug pellets. CN Patent No. ZL200910014471.7. (April 17, 2013)

  3. Zhenghong Wu  with co-inventors: Wu Yuantong, Li Yunman, Zhu Yilin. A traditional Chinese medicine composition for treating gout and its preparation and use. CN Patent No. ZL ZL201110278416.6. (April 17, 2013)

  4. Zhenghong Wu with co-inventors: Zhang Xiao, Gu Lin, Chen Qin,Zhang Huiting. Preparation of oleanolic acid osmotic pump tablet. CN Patent No. ZL201010596043.2. (October 23, 2012)

  5. Zhenghong Wu with co-inventors: Wang Bogang, Lu Junjun . A kind of breviscapine solution. Patent CN No. ZL200810122925.8. (June 9, 2010)

  6. Zhenghong Wu with co-inventors: Wang Bogang, Huang yuelun, Yu Bing. Preparation of celastrol liposomes. CN Patent No. ZL200810019653.9. (June 2, 2010)