QI, LIANWEN

Release date:2016-05-18  Release:

QI, LIANWEN

Professor of Pharmacognosy

PI in the State Key Laboratory of Natural Medicines

Director of Human Resources Department, China Pharmaceutical University

Phone: 025-86185559

Email: Qilw@cpu.edu.cn

Research Summary

(1) Discovery of bioactive components from Chinese Herbal Medicines: Professor QI’s research focuses on bioactive components discovery and quality evaluation of Chinese Herbal Medicines (CHMs). Dr. QI’s team has developed innovative strategies for analyzing complex components, discovering bioactive equivalent combinatorial components, and exploring underlying mechnisms for CHMs. (2) Metabolomic profiling of human diseases: Based on large clinical samples, the team have successfully developed a LC-Q-TOF/MS-based technical platform for characterization of metabolic fingerprint analysis of diseasesand metabolic regulation of CHMs. It is aimed to employ a comprehensive metabolomic evaluation for characterization of metabolic disturbances and discovery of diagnostic biomarkers in different clinical types of diseases.


Education

2009  Ph.D., Pharmacognosy, China Pharmaceutical University

2004  B.S., Traditional Chinese Medicine, Hunan University Of

Chinese Medicine

Academic Experience

2012/05-          Professor of Pharmacognosy, School of

Traditional Chinese Pharmacy, China

Pharmaceutical University

2011/01-2012/05  Associate Professor of Pharmacognosy,

School of Traditional Chinese Pharmacy,

China Pharmaceutical University

2013/07-2013/08  Visiting Scholar, Department of Anatomy,

The University of Hong Kong

2012/07-2012/09  Visiting Scholar, School of Medicine, The

University of Chicago

2009/09-2011/01  Post-doctor, School of Medicine, The

University of Chicago

2009/07-2011/01  Instructor of Pharmacognosy, School of

Traditional Chinese Pharmacy, China

Pharmaceutical University

Awards and Honors

2016 the 15th Fork Ying-Tong Education Foundation for Young Teachers in the Higher Education Institutions of China, the Fok Ying-Tong Education Foundation

2015 Grand Challenges 2015-Young Scientists Award, Ministry of Science and Technology of China

2014 The National Ten Thousand Talents Award, the Organization Department of the Central Committee

2014  Jiangsu Ten Preeminent Yong People Award, Youth Federation of Jiangsu Province

2013   First Prize of Natural Science Award of Ministry of Education of China, Ministry of Education of China

2013   Young and Middle-aged Leading Talents in Scientific and Technical Innovation, Ministry of Science and Technology of China

2012   National Excellent Young Scientist Award,  National Natural Science Foundation of China

2011   New Century Excellent Talents Award, Ministry of Education of China

2011  National Excellent Doctorial Dissertation Award, Ministry of Education of China; Academic Degrees Committee

Publications

  1. Fan Y#, Li Y#, Chen Y#, Zhao YJ, Liu LW, Li J, Wang SL, Alolga RN, Yin Y, Wang XM, Zhao DS, Shen JH, Meng FQ, Zhou X, Xu H, He GP, Lai MD, Li P*, Zhu W*, Qi LW*, Comprehensive metabolomic characterization of coronary artery diseases, J Am Coll Cardiol, 2016.

  2. Qi Lian-Wen*, Wang Chong-Zhi, Yuan Chun-Su*, Isolation and analysis of ginseng: advances and challenges, Natural Product Reports (IF=10.107), 2011, 28(3): 467-495 (Cover Article).

  3. Fan Yong#, Zhou Xin#, Xia Tian-Song#, Chen Zhuo, Li Jin, Liu Qun, Alolga Raphael N, Chen Yan, Lai Mao-De, Li Ping*, Zhu Wei*, Qi Lian-Wen*, Human plasma metabolomics for identifying differential metabolites and predicting molecular subtypes of breast cancer, Oncotarget (IF=6.359), 2016, 7(9): 9925-38.

  4. Lai Chang-Jiang-Sheng#Tan Ting#Zeng Su-LingXu Lin-RuQi Lian-Wen*Liu E-Hu*Li Ping*, An enzyme protocol for absolute quantification of analogues: application to specific protopanoxadiol-type ginsenosides, Green Chemistry (IF=8.02), 2015,17(4): 2580-2586.

  5. Huang Feng-Qing, Xie Jian, Sun Jian-Guo, Wang YueWei, Dong Xin, Qi Lian-Wen*, Zhang Bo*, Regioselective Synthesis of Carbonyl-Containing Alkyl Chlorides via Silver-Catalyzed Ring-Opening Chlorination of Cycloalkanols, Organic Letters (IF=6.364), 2016, 18 (4):684–687.

  6. Alolga Raphael N#, Fan Yong#, Zhang Gang#, Li Jin, Zhao Yi-Jing, Kakila Jimmy Lelu, Chen Yan*, Li Ping*, Qi Lian-Wen*, Pharmacokinetics of a multicomponent herbal preparation in healthy Chinese and African volunteers, Scientific Reports (IF=5.578), 2015, 5, 12961.

  7. Liu Kang, Mei Fan, Wang Yapu, Xiao Na, Yang Lele, Wang Yilei, Li Jia, Huang Fang, Kou Junping, Liu Baolin, Qi Lian-Wen*, Quercetin oppositely regulates insulin-mediated glucose disposal in skeletal muscle under normal and inflammatory conditions: The dual roles of AMPK activation, Molecular Nutrition & Food Research (IF=4.603), 2015, 60(3): 551-565.

  8. Cheng Xiao-Lan, Wan Jin-Yi, Li Ping*, Qi Lian-Wen*, Ultrasonic/microwave assisted extraction and diagnostic ion filtering strategy by liquid chromatography-quadrupole time-of-flight mass spectrometry for rapid characterization of flavonoids in Spatholobus suberectus, Journal of Chromatography A (IF=4.169), 2011, 1218, 5774-5786.

  9. Liu Ying, Shi Xiao-Wei, Liu E-Hu, Sheng Long-Sheng, Qi Lian-Wen*, Li Ping*, More accurate matrix-matched quantification using standard superposition method for herbal medicines, Journal of Chromatography A (IF=4.169), 2012, 1254, 43-50.

  10. Wan Jin-Yi#, Liu Peng#, Wang Huai-You, Qi Lian-Wen*, Wang Chong-Zhi, Li Ping*, Yuan Chun-Su. Biotransformation and metabolic profile of american ginseng saponins with human intestinal microflora by liquid chromatography quadrupole time-of-flight mass spectrometry. Journal of Chromatography A (IF=4.169), 2013, 1286, 83-92.