YANG, HUA

Release date:2016-05-19  Release:

YANG, HUA

Associate Professor of Pharmacognosy, School of Traditional Chinese Pharmacy

Assistant-to-Director in the State Key Laboratory of Natural Medicines, China Pharmaceutical University

Phone: 86-25-83271220

Email: yanghuacpu@126.com

Research Summary

Dr. Yang’s research focused on developing modern analytical strategies to analyze the chemical composition, pharmacokinetics of traditional Chinese medicine and natural products, including comprehensive two-dimensional chromatography, supercritical fluid chromatography or ultra-high performance liquid chromatography couple with mass spectrometry, etc. In addition, Dr. Yang also interested in the discovery of bioactive components from traditional Chinese medicine, and revealing their mechanism through molecular biology and system biology methods. Her researches have been successfully applied to the quality control and therapeutic of Salvia miltiorrhiza, Ginkgo biloba, Aconitum carmichaeli, etc.


Education

2008.09-2013.06Ph.D., Pharmacognosy, China Pharmaceutical University

2009.09-2011.02Research Visiting Scholar, Hong Kong Baptist University, Hong Kong

2004.09-2008.06B.S., Chinese Materia MedicaChina Pharmaceutical University

Academic Experience

2016.01-currentAssociate Professor, School of Traditional Chinese Pharmacy, China Pharmaceutical University

2015.04-currentVice Director, Department of Pharmacognosy, School of Traditional Chinese Pharmacy, China Pharmaceutical University

2013.07-2015.04Senior Research Scientist, School of Traditional Chinese Pharmacy, China Pharmaceutical University

Publications

1)Song HP, Chen J, Hong JY, Hao H, Qi LW, Lu J, Fu Y, Wu B, Yang H*, Li P*. A strategy for screening of high-quality enzyme inhibitors from herbal medicines based on ultrafiltration LC-MS and in silico molecular docking. Chem Commun (Camb), 2015, 51:1494-7. [IF=6.834]

2)Song HP, Wu SQ, Hao HP, Chen J, Lu J, Xu XJ, Li P*, Yang H*, A chemical family-based strategyfor uncovering hidden bioactivemolecules and multicomponentinteractions in herbal medicines, Sci Rep, 2016:23840. [IF=5.578]

3)Wu B, Song HP, Zhou X, Liu XG, Gao W, Dong X, Li HJ, Li P*, Yang H*,Screening of minor bioactive compounds from herbal medicines by in silico docking and the trace peak exposure methodsJ Chromatogr A, 2016, 1436:91-99. [IF=4.169]

4)Guo RZ1, Liu XG1, Gao W, Dong X, Fanali S, Li P, Yang H*, A strategy for screening antioxidants in Ginkgo biloba extract by comprehensive two-dimensional ultra-high performance liquid chromatographyJ Chromatogr A, 2015, 1422:147-154. [IF=4.169]

5)Liu XG, Qi LW, Fan ZY, Dong X, Guo RZ, Lou FC, Fanali S, Li P*, Yang H*. Accurate analysis of ginkgolides and their hydrolyzed metabolites by analytical supercritical fluid chromatography hybrid tandem mass spectrometry. J Chromatogr A, 2015, 1388:251-8. [IF=4.169]

6)Wang ST1, Gao W1, Fan YX, Liu XG, Liu K, Du Yuan, Wang LL, Li HJ, Li P*, Yang H*, Phenol profiles and antioxidant capacities of BistortRhizoma (Polygonum bistorta L.) extracts, RSC Adv, 2016, 6: 27320-27328. [IF=3.840]

7)Yang H, Ding Y, Gao W, Qi LW, Cao J*, Li P*, Efficient separation of tanshinones bypolyvinylpyrrolidone-stabilizedgraphene-modified micellar electrokineticchromatography, Electrophoresis, 2015, 36:2874-2880.[IF=3.028]

8)Yang H, Ding Y, Cao J*, Li P*. Twenty-one years of microemulsion electrokinetic chromatography (1991-2012): A powerful analytical tool. Electrophoresis, 2013, 34:1273-1294.[IF=3.028]

9)Yang H1, Gao W1, Liu L, Liu K, Liu EH, Qi LW*, Li P*, Discovery of characteristic chemical markers for classification of aconite herbs by chromatographic profile and probabilistic neural network, J Pharm Biomed Anal, 2015, 115: 10-19. [IF=2.979]

10)Yang H, Liu L, Gao W, Liu K, Qi LW*, Li P*. Direct and comprehensive analysis of ginsenosides and diterpenealkaloids in Shenfu injection by combinatory liquidchromatography–mass spectrometrictechniques. J Pharm Biomed Anal, 2014, 92:13-21. [IF=2.979]