YIN, ZHIQI

Release date:2016-05-19  Release:

YIN, ZHIQI

Associate Professor of Natural Medicinal Chemistry

Vice Directorof Department of Natural Medicinal Chemistry

School of Traditional Chinese Medicine

Phone: 86-25-86185371

Email: cpu-yzq@cpu.edu.cn


Research Summary

Professor YIN’s research focuses on discovery of novel natural constituents, biological evaluation anddevelopment of health food from natural medicines and Traditional Chinese Medicines. Especially she has made some excellent progress in discovery of small molecular necrosis-targetingcompound for the treatment of residual tumor after chemotherapies and noninvasive assessment of myocardial viability, as well as discovery of lead compound in the treatment of metabolic diseases (diabetes, hyperlipidemia, obesity and non-alcoholic fatty liver disease). She has published over 50SCI papers, and their work were financially supported by the National Natural Science Foundation of China and Jiangsu Provincial Projects.

Education

2002       Ph.D., Medicinal Chemistry, China Pharmaceutical University

1997       B.S., Pharmaceutical Chemistry of Traditional Chinese Medicine, China Pharmaceutical University

Academic Experience

2014-      Associate Professor of Natural Medicinal Chemistry, China Pharmaceutical University

2013-2014  Visiting Scholar of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, USA

2006-2013  Associate Professor of Natural Medicinal Chemistry, China Pharmaceutical University

2004-2005  Lecture of Natural Medicinal Chemistry, China Pharmaceutical University

2003-2004  Visiting Scholar of Biology, The Hong Kong University of Science and Technology

2002-2003  Lecture of Natural Medicinal Chemistry, China Pharmaceutical University

Awards and Honors

2014       The Third Top Ten Youth Star of Traditional Chinese Medicine in Jiangsu Province, Jiangsu Provincial Chinese Medicine Institute

2012       High-level Talents of the Ninth Batch of “Six Talent Peaks” in Jiangsu Province, Jiangsu ProvincialEconomic and Information Commission

2010       Outstanding young teachers of Qing Lan Projectof Jiangsu Colleges and Universities,Jiangsu Provincial Department of Education

Publications

  1. Zhiqi Yin*#, ShuLe Yu#, YuJian Wei, Lin Ma, ZhengFeng Wu, Lei Wang, QingWen Zhang,Ming Zhao, WenCai Ye, ChunTao Che, Jian Zhang*. C21 steroidal glycosides from Cynanchum stauntonii induce apoptosis in HepG2 cells. Steroids, 2016,106: 55-61

  2. Cong Wang,Qiaomei Jin,Shengwei Yang,Dongjian Zhang,Qin Wang,Jindian Li,Shaoli Song,Ziping Sun, Yicheng Ni, Jian Zhang*, Zhiqi Yin*. Synthesis and Evaluation of131I Skyrin as a Necrosis Avid Agent forPotential Targeted Radionuclide Therapy of Solid Tumors. Mol. Pharmaceutics, 2016, 13(1): 180-189

  3. Jindian Li,Jian Zhang,Shengwei Yang,Cuihua Jiang,DongJian Zhang,Qiaomei Jin,Qin Wang,Cong Wang,Yicheng Ni, Zhiqi Yin*, Shaoli Song*. Synthesis and Preclinical Evaluation of Radioiodinated Hypericin Dicarboxylic Acid as a Necrosis Avid Agent in Rat Models of Induced Hepatic, Muscular, and Myocardial Necroses. Mol. Pharmaceutics, 2016, 13(1): 232-240

  4. Kuiniu Zhu, Cuihua Jiang, Yushan Tian, Na Xiao, Zhengfeng Wu, Yonglan Ma, Zi Lin, Shengzuo Fang, Xulan Shang, Kang Liu, Jian Zhang, Baolin Liu*, Zhiqi Yin*. Two triterpeniods from Cyclocarya paliurus (Batal) Iljinsk (Juglandaceae) promote glucose uptake in 3T3-L1 adipocytes: the relationship to AMPK activation. Phytomedicine, 2015, 22(9):837-846

  5. Yun Ji, Cuihua Jiang, Xueli Zhang, Wei Liu, Meng Gao, Yue Li, Junhu Wang, Qingqing Wang, Ziping Sun, Xiao Jiang, Nan Yao, Xiaoning Wang, Zhijun Fang, Zhiqi Yin*, Yicheng Ni, Jian Zhang*. Necrosis-targeted combinational theragnostic approach to treat cancer. Oncotarget, 2014, 5(10): 2934-2946