ZHANG, CHUNFENG

Release date:2016-05-19  Release:


 

ZHANG, CHUNFENG

Professor of Chinese Medicine

School of Chinese Medicine

Phone: 86-25-86185129

Email: zhangchunfeng@cpu.edu.cn

Research Summary

Professor ZHAGN’s research focuses on the the development of new drugs from Chinese medicine, especially effective part, such as total flavonoids aglycone from Flos Genkwa in curing immunity inflammation. At the same time, she more interested in intestinal absorption of flavonoids and processing of Chinese medicine.She charged3 national research projects, 1 provincial research projects, 5 other projects and published 59 articles and 2 books.

Education

2007 Ph.D., Chinese medicine, China Pharmaceutical University

2004 M.S.,  Chinese medicineShandong University of TCM

1990 B.S.,   Chinese medicineHeilongjiang University of TCM

Academic Experience

2015-      Professor of Chinese medicine, China Pharmaceutical University

2013-2014 Visiting Scholar, University of Chicago

2007-2015 Associate professor of Chinese medicine, China Pharmaceutical University

Publications

1Liang Yan(#)Xiaolin YangZhaoqing MengYongliang YuanWei XiaoZhenzhong WangWenze HuangZhonglin Yang*(*)Chunfeng Zhang*.(*)Simultaneous quantification of Akebia saponin D and its five metabolites in human intestinal bacteria using ultra-performance liquid chromatography triple quadrupole mass spectrometry.J Chromatogr B Analyt Technol Biomed Life Sci2014971971):81-88SCI

2Su-Li Zhang(#)Hui LiXin HeRun-Qi ZhangYu-He SunChun-Feng Zhang(*)Chong-Zhi WangChun-Su YuanAlkaloids from Mahonia bealei posses anti-H+/K+-ATPase and anti-gastrin effects on pyloric ligation-induced gastric ulcer in ratsPhytomedicine20142111):1356-1363SCI

3Yu-He SUN(#)Xin HEXiao-Lin YANGCui-Lan DONGChun-Feng ZHANG(*)Zi-Jing SONGMing-Xing LUZhong-Lin YANGPing LIAbsorption characteristics of the total alkaloids from Mahonia bealei in an in situ single-pass intestinal perfusion assayChinese Journal of Natural Medicines2014127):554-560SCI

4Cui-Ping Jiang(#)Xin HeXiao-Lin YangSu-Li ZhangHui LiZi-Jing SongChun-Feng Zhang(*)Zhong-Lin YangPing LiChong-Zhi WangChun-Su YuanAnti-rheumatoid arthritic activity of flavonoids from Daphne genkwaPhytomedicine2014216):830-837SCI

5Chun-Feng Zhang(#)(*)Su-Li ZhangXin HeXiao-Lin YangHai-Tao WuBao-Qin LinCui-Ping JiangJun WangChun-Hao YuZhong-Lin YangChong-Zhi WangPing LiChun-Su YuanAntioxidant effects of Genkwa flos flavonoids on Freunds adjuvant-induced rheumatoid arthritis in ratsJournal of Ethnopharmacology20141533):793-800SCI

6Chen, Lvyi(#)Zhao, LeiZhang, Chunfeng(*)Lan, Zhou(*)Protective Effect of p-Cymene on Lipopolysaccharide-Induced Acute Lung Injury in MiceInflammation2014372):358-364SCI

7Cui-Ping Jiang(#)Xin HeXiao-Lin YangSu-Li ZhangHui LiZi-Jing SongChunfeng Zhang(*)Zhong-Lin YangPing LiChong-Zhi WangChun-Su YuanAnti-rheumatoid arthritic activity of flavonoids from Daphne genkwaPhytomedicine2014216):830-837SCI

8Changrun Guo(#)Lu LiXiaolin YangZhaoqing MengFei LiChunfeng Zhang(*)Zhonglin Yang(*)Protective effects of timosaponin B-II on high glucose-induced apoptosis in human umbilical vein endothelial cellsEnvironmental Toxicology and Pharmacology2014371):37-44SCI

9Jiang, Cui-Ping(#)He, XinYang, Xiao-LinZhang, Su-LiLi, HuiSong, Zi-JingZhang, Chun-Feng(*)Yang, Zhong-LinLi, PingIntestinal Absorptive Transport of Genkwanin from Flos genkwa Using a Single-Pass Intestinal Perfusion Rat ModelAmerican Journal of Chinese Medicine2014422):349-359SCI

10Qi, Dongli(#)Yang, XiaolinChen, JingLi, FeiShi, XiupuZhang, Chunfeng(*)Yang, Zhonglin(*)Det ermination of chikusetsusaponin V and chikusetsusaponin IV in rat plasma by liquid chromatography-mass spectrometry and its application to a preliminary pharmacokinetic studyBiomedical Chromatography20132711):1568-1573SCI

11De JI(#)Yun-Fei LIUQiao-Han WANGChun-Feng ZHANG(*)Zhong-Lin YANG(*)Isolation, structurecharacterization and quantification of related impurities in asperosaponin VIChinese Journal of Natural Medicines2013114):419-426SCI

12Yang, Xiaolin(#)Li, Fei(*)Yang, YananShen, JinyangZou, RunZhu, PanpanZhang, Chunfeng(*)Yang , ZhonglinLi, PingEfficacy and Safety of Echinacoside in a Rat Osteopenia ModelEvidence-BasedComplementary and Alternative Medicine2013248):26-36SCI

13Han, De-en(#)Zheng, YiChen, XijingHe, JiakeZhao, DiYang, ShuoyeZhang, ChunfengYang,Zhonglin(*)Identification and Characterization of Human UDP-glucuronosyltransferases Responsible for the In Vitro Glucuronidation of Salvianolic Acid ADrug Metabolism and Pharmacokinetics2012276):579-5853SCI

14Lvyi Chen(#)Huafeng YinZhou LanShuwei MaChunfeng Zhang(*)Zhonglin Yang(*)Ping LiBaoqin LinAnti-hyperuricemic and nephroprotective effects of Smilax china L.Journal of Ethnopharmacology20111352):399-405SCI

15Fei Li(#)Yanan YangPanpan ZhuWeina ChenDongli QiXiupu ShiChunfeng Zhang(*)Zhonglin Yang(*) Ping LiEchinacoside promotes bone regeneration by increasing OPG/RANKL ratio in MC3T3-E1 cellsFitoterapia2012838):1443-1450SCI

16Shi, Xiupu(#)Liao, ShaMi, HuijuanGuo, ChangrunQi, DongliLi, FeiZhang, Chunfeng(*)Yang, Zhonglin(*)Hesperidin Prevents Retinal and Plasma Abnormalities in Streptozotocin-Induced Diabetic RatsMolecules20121711):12868-1288115SCI

17Chen, Lvyi(#)Lan, ZhouZhou, YongqiangLi, FeiZhang, XinZhang, Chunfeng(*)Yang, Zhonglin(*)Li, PingAstilbin Attenuates Hyperuricemia and Ameliorates Nephropathy in Fructose-Induced Hyperuricemic RatsPlanta Medica20117716):1769-17737SCI

18De Ji(#)Yue WuBin ZhangChun-Feng Zhang(*)Zhong-Lin Yang(*)Triterpene saponins from the roots of Dipsacus asper and their protective effects against the Aβ25–35 induced cytotoxicity in PC12 cellsFitoterapia2012835):843-848SCI

19Wu, Yue(#)Ji, DeLiu, YunfeiZhang, Chunfeng(*)Yang, Zhonglin(*)Industrial-Scale Preparation of Akebia Saponin D by a Two-Step Macroporous Resin Column SeparationMolecules2012177):7798-78090SCI

20Xing Yu(#)Lin-na WangLin MaRan YouRan CuiDe JiYue WuChun-feng ZhangZhong-lin YangHui Ji(*)Akebia saponin D attenuates ibotenic acid-induced cognitive deficits and pro-apoptotic response in rats: Involvement of MAPK signal pathwayPharmacology Biochemistry and Behavior20121013):479-486SCI

21Chunfeng Zhang(#)Zhonglin Yang*(*)Jiabo Luo*(*)Effects of cinnamene enhancers on transdermal delivery of ligustrazine hydrochlorideEuropean Journal of Pharmaceutics and Biopharmaceutic2007672):413-419SCI

22Chunhao Yu(#)Xiao-Dong WenZhiyu ZhangChun-Feng ZhangXiaohui WuXin HeYang LiaoNingning WuChong-Zhi WangWei DuTong-Chuan HeChun-Su YuanAmerican ginseng significantly reduced the progression of high-fat-diet-enhanced colon carcinogenesis in ApcMin/+miceJournal of Ginseng Research20152111):168-178SCI

23Zhang, Chun-feng(#)Yang, Zhong-lin(*)Luo, Jia-bo(*)Effects of enantiomer and isomer permeation enhancers on transdermal delivery of ligustrazine hydrochloridePharmaceutical Development and Technology2006114):417-42410SCI

24Chunhao Yu(#)Xiao-Dong WenZhiyu ZhangChun-Feng ZhangXiao-Hui WuAdiba MartinWei DuTong-Chuan HeChong-Zhi WangChun-Su Yuan(*)American ginseng attenuates azoxymethane/dextran sodium sulfate-induced colon carcinogenesis in miceJournal of GinsengResearch2015391):14-21SCI

25Zhiyu Zhang(#)Zejuan LiXiaohui WuChun-Feng ZhangTyler CalwayTong-Chuan HeWei DuJianjun ChenChong-Zhi WangChun-Su Yuan(*)TRAIL pathway is associated with inhibition of colon cancer by protopanaxadiolJournal of Pharmacological Sciences20151271):83-91SCI

26Ji, De(#)Zhang, ChunfengLi, JingzhiYang, HaoweiShen, JingyangYang, Zhonglin(*)A New Iridoid Glycoside from the Roots of Dipsacus asperMolecules2012172):1419-14245SCI

27Fei Li(#)Xiaolin YangYanan YangChangrun GuoChunfeng Zhang(*)Zhonglin Yang(*)Ping LiAntiosteoporotic activity of echinacoside in ovariectomizedratsPhytomedicine2013206):549-557SCI

28Li, Fei(#)Yang, XiaolinYang, YananLi, PingYang, Zhonglin(*)Zhang, Chunfeng(*)Phospholipid complex as an approach for bioavailability enhancement of echinacoside.Drug Development and Industrial Pharmacy2015225):1-8SCI

29Guo, Changrun(#)Han, FengyuZhang, ChunfengXiao, Wei(*)Yang, Zhonglin(*)Protective Effects of Oxymatrine on Experimental Diabetic NephropathyPlanta Medica2014804):269-2761SCI

30Changrun Guo(#)Chunfeng Zhang(#)Lu LiZhenzhong WangWei Xiao(*)Zhonglin Yang(*)Hypoglycemic and hypolipidemic effects of oxymatrine in high-fat diet and streptozotocin-induced diabetic ratsPhytomedicine2014216):807-814SCI