PENG, SIXUN

Release date:2016-06-06  Release:

PENG, SIXUN

Professor of Medicinal Chemistry

Academician of Chinese Academy of Engineering

Institute of Pharmaceutical Sciences

Phone: 86-25-83309911

Research Summary

In early 1960s, Prof. Peng studied on centrol depressants.Later he studied on non-steroidal anti-inflammatory drugs.After 1980s,he was meanly engaged in cardiovascular drugs,particularly interested in those compounds acting on calcium or potassium ion channels.One of the research projectsStudies Based on Molecular Modification and Biological Activity of Chinese Medicinal Materialshad been carried out for more than 10 years.Several compounds showed good cardiovascular effects to be further studied.One of such compounds,86017,was a multiple ion channel blocker with anti-arrhythmic activity,preclinical studies had been finished ,obtained 4 countries` patents.Another compounds CPU23 had been proved to be a novel calcium antagonist with hypotensive activity,its binding site probably was on the DHP receptor of L-type calcium ion channel by molecular modeling analysis.Furthermore,a new potassium ion channel blocker BTHP was also identified.

Education

1950  M.S.,  Medicinal Chemistry  Columbia University,U.S.A

1942  B.S.,   Pharmacy  National School of Pharmacy

Academic Experience

1978-    Professor of Medicinal Chemistry, China Pharmaceutical University

1951-1977  Associate Professor of Medicinal Chemistry, Nanjing College of Pharmacy

Awards and Honors

1993  Progress Award in Science and Technology  Ministry of Education

1995  Progress Award in Science and Technology  Shandong Province

1998  Progress Award in Science and Technology  Jiangsu Province

1999  HLHL Prize of Progress in Science and Technology

2007  Distinguished Award of China Pharmaceutical Association