TONG, YUE

Release date:2016-06-06  Release:



Tong, Yue

Associate Professor of Microbiology and Biochemical Pharmacy

School of Life Science and Technology

Phone: 86-25-83271367

Email: tongycpu@163.com

Research Summary

Dr Tong’s research focuses onBiological Drug Research and Development and Modification of Protein Drugs. She presided over projects of the National Natural Science Foundation, the Natural Science Foundation of Jiangsu Province, Hi-Tech Research and Development Program of China-863 Program and the Fundamental Research Funds for the Central Universities.

Education

2010       Ph.D., Microbiology and Biochemical Pharmacy, China Pharmaceutical University

2005    B.S., Biotechnology,China Pharmaceutical University

Academic Experience

2015-   Associate Professor of Microbiology & Biochemical Pharmacy, China Pharmaceutical University

2010-2015 Lecturer of Microbiology & Biochemical PharmacyChina Pharmaceutical University

Publications

  1. Yuelin Kong, Yue Tong (Co-first author), Chen Chen, Mingming Gao, Xiangdong Gao*, Wenbing Yao*. Alleviation of high-fat diet-induced atherosclerosis and glucose intolerance by a novel GLP-1 fusion protein in ApoE−/− mice[J]. Endocrine, 2016: 1-10. DOI: 10.1007/s12020-015-0831-3

  2. Mingming Gao, Yue Tong(Co-first author), Xiangdong Gao*, Wenbing Yao*, Development of a C-terminal Site-specific PEGylated Analog of GLP-1 with Improved Anti-diabetic Effects in Diabetic Mice,Drug Develop Res, 2013,74(3):186-193

  3. Mingming Gao, Yue Tong(Co-first author), Xiangdong Gao*, Wenbing Yao*, PEGylation-aided Refolding of Globular Adiponectin,World J Microb Biot, 2013, 29(8):1525-1530

  4. Mingming Gao, Yue Tong(Co-first author), Hong Tian, Xiangdong Gao*, Wenbing Yao*, Recombinant production of mGLP-1 by coupling of refolding and intein-mediated self-cleavage (CRIS),Appl Microbiol Biotechnol,2012,96(5):1283- 1290

  5. Yue Tong, Kai Zhong, Hong Tian, Xiangdong Gao*, Xiangyang Xu, Xiaojin Yin, Wenbing Yao*,Characterization of a monoPEG20000-Endostar, Int J Biol Macromol,2010,46(3):331-336

  6. Yuelin Kong, Yue Tong, Mingming Gao, Chen Chen, Xiangdong Gao*, Wenbing Yao*. Linker Engineering for Fusion Protein Construction: Improvement and Characterization of a GLP-1 Fusion Protein[J]. Enzyme and Microbial Technology, 2016,82:105-109

  7. Yu Zhang, Yue Tong, Mingming Gao,Chen Luo, Xiaoda Song,Xiangdong Gao*, Wenbing Yao*.Expression, purification and characterization of a vascular endothelial growth factor fusion protein. Biotechnology Letters. 2016,DOI: 10.1007/s10529-016-2081-8

  8. Mingming Gao, Yue Tong, Xiangdong Gao*, Wenbing Yao*, A mutated glucagon-like peptide-1 with improved glucose-lowering activity in diabetic mice,J Pharm Pharmacol, 2013,65(4):539-546

  9. Mingming Gao, Yue Tong , Wen Li , Xiangdong Gao* , Wenbing Yao*, Improving the anti-diabetic activity of GLP-1 by fusion with globular adiponectin, Artif Cell Blood Substit Bio, 2013,41(3):159-164

  10. Mingming Gao, Yuhao Jin, Yue Tong, Hong Tian, Xiangdong Gao*, Wenbing Yao*, A site-specific PEGylated analog of exendin-4 with improved pharmacokinetics and pharmacodynamics in vivo,J Pharm Pharmacol,2012, 64(11):1646-1653

  11. Xiaowei Qian, Hongxia Dong, Hong Tian, Yue Tong, Linfeng Guo, Xiaojing Hu, Xiangdong Gao*, Wenbing Yao*.Characterization of a site-specific PEGylated analog of exendin-4 and determination of the PEGylation site. International Journal of Pharmaceutics, 2013, 454(1):553-558