ZHOU, JINPEI
Professor of Medicinal Chemistry
School of Pharmacy
Phone: 13951694488
Email: jpzhou668@163. com
Research Summary
Professor Zhou has been studying onthe molecular design and synthesis of novel drugs, which has been endowed with independent intellectual property rights. He is also expert and reviewer of domestic and foreign funds, SCI Journal papers. Professor Zhou has applied for 14invention patents, published more than 50research papers
Education
1999 Ph.D., Medicinal Chemistry, China Pharmaceutical University
1989 M.S., Medicinal Chemistry, China Pharmaceutical University
1986 B.S., Medicinal Chemistry, Nanjing Pharmaceutical College
Academic Experience
2010- Professor of Medicinal Chemistry, China Pharmaceutical University
Awards and Honors
2000 Servier Award of Medicinal Chemistry, China
Publications
Xueting Cai, Jie Yang , Jinpei Zhou, Wuguang Lu, Chunping Hua, Zhenhua Gu, Jiege Huo ,Xiaoning Wang, Peng Cao. Synthesis and biological evaluation of scopoletin derivatives. Bioorganic & Medicinal Chemistry,21 (2013),84-92.
Xiong Zhu, Jinpei Zhou*,, Yan Zhu, Xiaowen Hu, Yuemin Bian, Xinting Hu, Zhuo Tao,Cong Gao and Wenlong Huang. Synthesis and Biological Activities of Sulfinyl Acetamide Derivatives forNarcolepsy Treatment.Letters in Drug Design & Discovery, 2013, 10, 266-270
Wukun Liu, Jie Hua, Jinpei Zhou*, Huibin Zhang, Haiyang Zhu, Yanhua Cheng, Ronald Gust. Synthesis and in vitro antitumor activity of novel scopoletin derivatives. Bioorganic & Medicinal Chemistry Letters,22 (2012), 5008-5012
Wukun Liu, Jinpei Zhou*, Tong Zhang, Huibin Zhang, Haiyang Zhu, Yanhua Cheng,Ronald Gust. Synthesis and biological evaluation of cyanoguanidine derivatives of loratadine. Bioorganic & Medicinal Chemistry Letters, 22 (2012), 6076-6080.
Jinpei Zhou, Lei Wang, Lijuan Wei, Yu Zheng, Huibin Zhang, Yubin Wang, Peng Cao, Ao Niu, Jing Wangand Yue Dai.Synthesis and Antitumor Activity of Scopoletin Derivatives. Letters in Drug Design & Discovery, 2012, 9(4), 397-401
Wukun Liu, Jinpei Zhou*, Tong Zhang, Haiyang Zhu, Hai Qian, Huibin Zhang, Wenlong Huang,Ronald Gust. Design and synthesis of thiourea derivatives containing a benzo[5,6]cyclohepta[1,2-b]pyridine moiety as potential antitumor and anti-inflammatory agents. Bioorganic & Medicinal Chemistry Letters, 2012, 22: 2701-2704
Wukun Liu, Jinpei Zhou#, Yu Zheng, Fan Qi, Huibin Zhang, Hai Qian, Jing Wang1,Yanhua Cheng and Ronald Gust. Design, Synthesis and Antiproliferative Activity of 2-Acetamidothiazole-5-carboxamide Derivatives. Medicinal Chemistry, 2012, 8, 587-594
Wukun Liu, Jinpei Zhou*, Fan Qi, Kerstin Bensdorf, Zhiyu Li, Huibin Zhang, Hai Qian,Wenlong Huang, Xueting Cai, Peng Cao, Anja Wellner, and Ronald Gust. Synthesis and Biological Activities of 2-Amino-thiazole-5-carboxylic Acid Phenylamide Derivatives. Arch. Pharm. Chem. Life Sci. 2011, 344, 451–458 451
Wukun Liu, Jinpei Zhou*, Kerstin Bensdorf , Huibin Zhang, Haoran Liu, YubinWang , Hai Qian,Yanchun Zhang, Anja Wellner, Gerhard Rubner, Wenlong Huang, Cancheng Guo, Ronald Gust. Investigations on cytotoxicity and anti-inflammatory potency of licofelone derivatives. European Journal of Medicinal Chemistry, 2011, 46, 907-913
Wukun Liu, Jinpei Zhou*, Huibin Zhang, Hai Qian, Jiahan Yin, Kerstin Bensdorf and Ronald Gust. Synthesis and Biological Evaluation of Licofelone Derivatives as Anticancer and Anti-inflammatory Agents. Letters in Drug Design & Discovery, 2011, 8, 911-917
Jinpei Zhou, Hai Qian, Huibin Zhang, Hui Gao, Wenlong Huang, Xiaoyun Zhu, Shuaijian Ni, and Chuntao Zhang. Design, Synthesis and Biological Evaluation of Benzopyran Derivatives as KATP Channel Openers. Letters in Drug Design & Discovery, 2010, 7(6), 415-420
Jinpei Zhou, Shuaijian Ni, Huibin Zhang, Hai Qian, Yushi Chi, Wenlong Huang, Lu Yu, Xiaowen Hu and Wei Chen. Synthesis and Bioactivity Evaluation of Dipeptidyl Peptidase IV Resistant Glucagon-like Peptide-1 Analogues. Protein and Peptide Letter, 2010, 17(10), 1290-1295
Hai Qian, Wei Chen, Xiaoyan Zhang, Huibin Zhang, Jinpei Zhou*, Wenlong Huang, Jing Jin and Dongyan Dai.Synthesis and Biological Evaluation of Dihydroisoquinoline-2(1H)-Carbothioamide Derivatives as TRPV1 Antagonists. Letters in Drug Design & Discovery, 2010, 7(4): 235-237
Yanchun Zhang, Jinpei Zhou*, Weihong Pan, Xiaoming Wu, and Shuai Wang.Synthesis and Biological Study of 3-Butyl-1-(2,6-dichlorophenyl)-1H-[1,2,4]triazol-5(4H)-one Derivatives as Anti-hypertension Drugs. Letters in Drug Design & Discovery, 2010, 7(1): 18-22
Hai Qian, Wei Chen, Jin Pei Zhou*, Wen Long Huang, Hui Bin Zhang, Jing Jin. Total Synthesis of endothelin 1 by microwave-assisted solid phase method. Chinese Chemical Letters, 2010, 21:388-390
Hai Qian, Zhixian Fu, Huibin Zhang, Jinpei Zhou*, Wenlong Huang, Jing Jin, Wei Chen and Dongyan Dai.Synthesis and Biological Evaluation of Capsaicin Derivatives as Analgesia Drugs. Letters in Drug Design & Discovery, 2010, 7(2), 122-127
Jinpei Zhou, Xiaowen Hu, Huibin Zhang, Hai Qian, Wenlong Huang, Fan Qi and Yanchun Zhang. Synthesis and Biological Evaluation of 5,6-Dihydro-benzo[c] acridin-7-ol Derivatives as Anti-Alzheimer’s Disease Drugs. Letters in Drug Design & Discovery, 2009,6(8): 623-628
Jinpei Zhou, Huibin Zhang, Hai Qian, Liang Lin, Wenlong Huang and Shuaijian Ni. Synthesis and Biological Evaluation of Aromatase Inhibitors. Letters in Drug Design & Discovery, 2009,6(3): 181-185
ZHANG Hui-bin, ZHANG Ya-an, WU Guan-zhong, ZHOU Jin-pei*. HUANG Wen-long, HU Xiao-wen. Synthesis and biological evaluation of sulfonylurea and thiourea derivatives substituted with benzenesulfonamide groups as potential hypoglycemic agents. Bioorganic & Medicinal Chemistry Letters, 2009,19(6):1740-1744
Xiangyang Sha, Huibin Zhang, Wenlong Huang, Jinpei Zhou*, Yinghong Zhou. Design and Synthesis of Thiazolidinedione Derivatives as Selective PPARγ Modulators. Letters in Drug Design & Discovery, 2009,6(3): 224-227