ZHOU, JINPEI

Release date:2016-06-06  Release:




ZHOU, JINPEI

Professor of Medicinal Chemistry


School of Pharmacy

Phone: 13951694488

Email: jpzhou668@163. com

Research Summary

Professor Zhou has been studying onthe molecular design and synthesis of novel drugs, which has been endowed with independent intellectual property rights. He is also expert and reviewer of domestic and foreign funds, SCI Journal papers. Professor Zhou has applied for 14invention patents, published more than 50research papers


Education

1999       Ph.D., Medicinal Chemistry, China Pharmaceutical University

1989       M.S.,  Medicinal Chemistry, China Pharmaceutical University

1986       B.S.,   Medicinal Chemistry, Nanjing Pharmaceutical College


Academic Experience

2010-      Professor of Medicinal Chemistry, China Pharmaceutical University

Awards and Honors

2000       Servier Award of Medicinal Chemistry, China

Publications

  1. Xueting Cai, Jie Yang , Jinpei Zhou, Wuguang Lu, Chunping Hua, Zhenhua Gu, Jiege Huo ,Xiaoning Wang, Peng Cao. Synthesis and biological evaluation of scopoletin derivatives. Bioorganic & Medicinal Chemistry,21 (2013),84-92.

  2. Xiong Zhu, Jinpei Zhou*,, Yan Zhu, Xiaowen Hu, Yuemin Bian, Xinting Hu, Zhuo Tao,Cong Gao and Wenlong Huang. Synthesis and Biological Activities of Sulfinyl Acetamide Derivatives forNarcolepsy Treatment.Letters in Drug Design & Discovery, 2013, 10, 266-270

  3. Wukun Liu, Jie Hua, Jinpei Zhou*, Huibin Zhang, Haiyang Zhu, Yanhua Cheng, Ronald Gust. Synthesis and in vitro antitumor activity of novel scopoletin derivatives. Bioorganic & Medicinal Chemistry Letters,22 (2012), 5008-5012

  4. Wukun Liu, Jinpei Zhou*, Tong Zhang, Huibin Zhang, Haiyang Zhu, Yanhua Cheng,Ronald Gust. Synthesis and biological evaluation of cyanoguanidine derivatives of loratadine. Bioorganic & Medicinal Chemistry Letters, 22 (2012), 6076-6080.

  5. Jinpei Zhou, Lei Wang, Lijuan Wei, Yu Zheng, Huibin Zhang, Yubin Wang, Peng Cao, Ao Niu, Jing Wangand Yue Dai.Synthesis and Antitumor Activity of Scopoletin Derivatives. Letters in Drug Design & Discovery, 2012, 9(4), 397-401

  6. Wukun Liu, Jinpei Zhou*, Tong Zhang, Haiyang Zhu, Hai Qian, Huibin Zhang, Wenlong Huang,Ronald Gust. Design and synthesis of thiourea derivatives containing a benzo[5,6]cyclohepta[1,2-b]pyridine moiety as potential antitumor and anti-inflammatory agents. Bioorganic & Medicinal Chemistry Letters, 2012, 22: 2701-2704

  7. Wukun Liu, Jinpei Zhou#, Yu Zheng, Fan Qi, Huibin Zhang, Hai Qian, Jing Wang1,Yanhua Cheng  and Ronald Gust. Design, Synthesis and Antiproliferative Activity of 2-Acetamidothiazole-5-carboxamide Derivatives. Medicinal Chemistry, 2012, 8, 587-594

  8. Wukun Liu, Jinpei Zhou*, Fan Qi, Kerstin Bensdorf, Zhiyu Li, Huibin Zhang, Hai Qian,Wenlong Huang, Xueting Cai, Peng Cao, Anja Wellner, and Ronald Gust. Synthesis and Biological Activities of 2-Amino-thiazole-5-carboxylic Acid Phenylamide Derivatives. Arch. Pharm. Chem. Life Sci. 2011, 344, 451–458 451

  9. Wukun Liu, Jinpei Zhou*, Kerstin Bensdorf , Huibin Zhang, Haoran Liu, YubinWang , Hai Qian,Yanchun Zhang, Anja Wellner, Gerhard Rubner, Wenlong Huang, Cancheng Guo, Ronald Gust. Investigations on cytotoxicity and anti-inflammatory potency of licofelone derivatives. European Journal of Medicinal Chemistry, 2011, 46, 907-913

  10. Wukun Liu, Jinpei Zhou*, Huibin Zhang, Hai Qian, Jiahan Yin, Kerstin Bensdorf and Ronald Gust. Synthesis and Biological Evaluation of Licofelone Derivatives as Anticancer and Anti-inflammatory Agents. Letters in Drug Design & Discovery, 2011, 8, 911-917

  11. Jinpei Zhou, Hai Qian, Huibin Zhang, Hui Gao, Wenlong Huang, Xiaoyun Zhu, Shuaijian Ni, and Chuntao Zhang. Design, Synthesis and Biological Evaluation of Benzopyran Derivatives as KATP Channel Openers. Letters in Drug Design & Discovery, 2010, 7(6), 415-420

  12. Jinpei Zhou, Shuaijian Ni, Huibin Zhang, Hai Qian, Yushi Chi, Wenlong Huang, Lu Yu, Xiaowen Hu and Wei Chen. Synthesis and Bioactivity Evaluation of Dipeptidyl Peptidase IV Resistant Glucagon-like Peptide-1 Analogues. Protein and Peptide Letter, 2010, 17(10), 1290-1295

  13. Hai Qian, Wei Chen, Xiaoyan Zhang, Huibin Zhang, Jinpei Zhou*, Wenlong Huang, Jing Jin and Dongyan Dai.Synthesis and Biological Evaluation of Dihydroisoquinoline-2(1H)-Carbothioamide Derivatives as TRPV1 Antagonists. Letters in Drug Design & Discovery, 2010, 7(4): 235-237

  14. Yanchun Zhang, Jinpei Zhou*, Weihong Pan, Xiaoming Wu, and Shuai Wang.Synthesis and Biological Study of 3-Butyl-1-(2,6-dichlorophenyl)-1H-[1,2,4]triazol-5(4H)-one Derivatives as Anti-hypertension Drugs. Letters in Drug Design & Discovery, 2010, 7(1): 18-22

  15. Hai Qian, Wei Chen, Jin Pei Zhou*, Wen Long Huang, Hui Bin Zhang, Jing Jin. Total Synthesis of endothelin 1 by microwave-assisted solid phase method. Chinese Chemical Letters, 2010, 21:388-390

  16. Hai Qian, Zhixian Fu, Huibin Zhang, Jinpei Zhou*, Wenlong Huang, Jing Jin, Wei Chen and Dongyan Dai.Synthesis and Biological Evaluation of Capsaicin Derivatives as Analgesia Drugs. Letters in Drug Design & Discovery, 2010, 7(2), 122-127

  17. Jinpei Zhou, Xiaowen Hu, Huibin Zhang, Hai Qian, Wenlong Huang, Fan Qi and Yanchun Zhang. Synthesis and Biological Evaluation of 5,6-Dihydro-benzo[c] acridin-7-ol Derivatives as Anti-Alzheimer’s Disease Drugs. Letters in Drug Design & Discovery, 20096(8): 623-628

  18. Jinpei Zhou, Huibin Zhang, Hai Qian, Liang Lin, Wenlong Huang and Shuaijian Ni. Synthesis and Biological Evaluation of Aromatase Inhibitors. Letters in Drug Design & Discovery, 20096(3): 181-185  

  19. ZHANG Hui-bin, ZHANG Ya-an, WU Guan-zhong, ZHOU Jin-pei*. HUANG Wen-long, HU Xiao-wen. Synthesis and biological evaluation of sulfonylurea and thiourea derivatives substituted with benzenesulfonamide groups as potential hypoglycemic agents. Bioorganic & Medicinal Chemistry Letters, 2009196):1740-1744

  20. Xiangyang Sha, Huibin Zhang, Wenlong Huang, Jinpei Zhou*, Yinghong Zhou. Design and Synthesis of Thiazolidinedione Derivatives as Selective PPARγ Modulators. Letters in Drug Design & Discovery, 20096(3): 224-227