LIU, CHANG

Release date:2017-10-23  Release:主页英文版

Liu, Chang

Professor of Molecular Cell Biology

School of Life Science and Biotechnology

Phone: 86-25-86185443

Email: changliu@cpu.edu.cn


Research Summary

Professor Liu’s research focuses on the integration of energy metabolism and circadian clock. By using modern biological approaches and animal models, his study will help to better understand the molecular basis of the metabolic diseases from the view of chronobiology.


Education

2005 Ph.D., Pathophysiology, Institute of Molecular Medicine, Nanjing University

1999 B.S., Biochemistry and molecular biology, Department of Biochemistry, Nanjing University


Academic Experience

2017-     Professor, PhD supervisor, School of Life Science and Biotechnology, China Pharmaceutical University

2008-2016 Vice Dean, Professor, PhD supervisor, College of Life Sciences, Nanjing Normal University

Director of Jiangsu Key Laboratory of Molecular and Medical Biotechnology

2006-2008 Postdoctoral Research Fellow, Life Sciences Institute, University of Michigan


Awards and Honors

2014 National Science Fund for Excellent Young Scholars

2014 Distinguished Young Scholars of Jiangsu Province

2013 Six Talent Peaks Project of Jiangsu Province  

2012 “Top Young Talents Program” by the Organization Department of the CPC Central Committee

2011 “New Century Excellent Talents in University” by Ministry of Education of the People’s Republic of China


Major Publications

 ●Tao W, Chen S, Shi G, Guo J, Xu Y, & Liu C*. (2011) SWItch/sucrose nonfermentable (SWI/SNF) complex subunit BAF60a integrates hepatic circadian clock and energy metabolism. Hepatology, 54, 1410-1420. (IF=13.25)

 ●Chen S, Zhang W, Tang C, Tang X, Liu L, & Liu C*. (2014) Vanin-1 is a key activator for hepatic gluconeogenesis. Diabetes, 63, 2073-2085.(IF=8.68)

 ●Chen S, Ding Y, Zhang Z, Wang H, & Liu C*.(2014) Hyperlipidemia impairs the circadian clock and physiological homeostasis of vascular smooth muscle cells via the suppression of Smarcd1. Journal of Pathology,233, 159-169 (cover story). (IF=7.43)

 ●Chen S, Wen X, Zhang W, Wang C, Liu J & Liu C*.(2017) Hypolipidemic effect of oleanolic acid is mediated by miR-98-5p/PGC-1β axis in high-fat diet-induced hyperlipidemic mice. FASEB Journal, 31: 1085-1096. (IF=5.498)

 ●Zhang W, Wang P, Chen S, Zhang Z, Liang T & Liu C*.(2016) Rhythmic expression of miR-27b-3p targets the clock gene Bmal1 at the post-transcriptional level in the mouse liver. FASEB Journal, 30, 2151-2060. (IF=5.498)