Liu, Chang
Professor of Molecular Cell Biology
School of Life Science and Biotechnology
Phone: 86-25-86185443
Email: changliu@cpu.edu.cn
Research Summary
Professor Liu’s research focuses on the integration of energy metabolism and circadian clock. By using modern biological approaches and animal models, his study will help to better understand the molecular basis of the metabolic diseases from the view of chronobiology.
Education
2005 Ph.D., Pathophysiology, Institute of Molecular Medicine, Nanjing University
1999 B.S., Biochemistry and molecular biology, Department of Biochemistry, Nanjing University
Academic Experience
2017- Professor, PhD supervisor, School of Life Science and Biotechnology, China Pharmaceutical University
2008-2016 Vice Dean, Professor, PhD supervisor, College of Life Sciences, Nanjing Normal University
Director of Jiangsu Key Laboratory of Molecular and Medical Biotechnology
2006-2008 Postdoctoral Research Fellow, Life Sciences Institute, University of Michigan
Awards and Honors
2014 National Science Fund for Excellent Young Scholars
2014 Distinguished Young Scholars of Jiangsu Province
2013 Six Talent Peaks Project of Jiangsu Province
2012 “Top Young Talents Program” by the Organization Department of the CPC Central Committee
2011 “New Century Excellent Talents in University” by Ministry of Education of the People’s Republic of China
●Tao W, Chen S, Shi G, Guo J, Xu Y, & Liu C*. (2011) SWItch/sucrose nonfermentable (SWI/SNF) complex subunit BAF60a integrates hepatic circadian clock and energy metabolism. Hepatology, 54, 1410-1420. (IF=13.25)
●Chen S, Zhang W, Tang C, Tang X, Liu L, & Liu C*. (2014) Vanin-1 is a key activator for hepatic gluconeogenesis. Diabetes, 63, 2073-2085.(IF=8.68)
●Chen S, Ding Y, Zhang Z, Wang H, & Liu C*.(2014) Hyperlipidemia impairs the circadian clock and physiological homeostasis of vascular smooth muscle cells via the suppression of Smarcd1. Journal of Pathology,233, 159-169 (cover story). (IF=7.43)
●Chen S, Wen X, Zhang W, Wang C, Liu J & Liu C*.(2017) Hypolipidemic effect of oleanolic acid is mediated by miR-98-5p/PGC-1β axis in high-fat diet-induced hyperlipidemic mice. FASEB Journal, 31: 1085-1096. (IF=5.498)
●Zhang W, Wang P, Chen S, Zhang Z, Liang T & Liu C*.(2016) Rhythmic expression of miR-27b-3p targets the clock gene Bmal1 at the post-transcriptional level in the mouse liver. FASEB Journal, 30, 2151-2060. (IF=5.498)
