Cuishufang

Through integrating comprehensive technology of molecular cell biology, immunology and disease animal model, Dr. Cui’s research manly focused on the role of ubiquitin-like modification in regulating virus infection and immune/metabolic-related diseases, such as multiple sclerosis and inflammatory diseases etc. 

1.Lei Chu#, Li Qian#, Yu Chen, Shengnan Duan, Ming Ding, Wu Sun, Wei Meng, Juanjuan Zhu, Quanyi Wang, Haiping Hao, Chen Wang*, Shufang Cui*(2024): HERC5-catalyzed ISGylation potentiates cGAS-mediated innate immunity. Cell Reports.

2.Lei Chu#, Chenhui Li#, Yongxing Li, Qiuya Yu, Huansha Yu, Chunhui Li, Wei Meng , Juanjuan Zhu, Quanyi Wang, Chen Wang*, Shufang Cui* (2021): Perillaldehyde Inhibition of cGAS Reduces dsDNA-Induced Interferon Response. Frontiers in Immunology.

3.Qiuya Yu#, Lei Chu#, Yongxing Li, Quanyi Wang, Juanjuan Zhu, Chen Wang*, Shufang Cui* (2021): miR-23a/b suppress cGAS-mediated innate and autoimmunity. Cellular & Molecular Immunology.  

4.Shufang Cui#, Qiuya Yu#, Lei Chu, Ye Cui, Ming Ding, Quanyi Wang, Hongyun Wang, Yu Chen, Xing Liu*, Chen Wang* (2020): Nuclear cGAS Functions Non-Canonically to Enhance Antiviral Immunity via recruiting Methyltransferase Prmt5. Cell Reports.

5.Shufang Cui#, Xin Liao#, Chao Ye, Xin Yin, Minghui Liu, Yeting Hong, Mengchao Yu, Yanqing Liu, Hongwei Liang, Chen-Yu Zhang and Xi Chen* (2017): ING5 suppresses breast cancer progression and is regulated by miR-24. Molecular Cancer. 

The function and regulatory mechanism of UCRP modification in immune-related diseases