Chuweihua

Associate Professor, Department of Microbiology and Systems Biology, College of Life Science and Technology, China Pharmaceutical University, Master's tutor of Microbiology and Biochemical Pharmacy, Public Health and Preventive Medicine, Biology and Medicine. He is a permanent member of the Chinese Society for Microbiology, a member of the American Society for Microbiology, a member of the International Society for Applied Microbiology, and a member of the Jiangsu Biochemical Society. He graduated from Nanjing Agricultural University with a PhD degree in Animal Medicine, which is a national key discipline; he was a postdoctoral researcher in the Department of Bioengineering, School of Chemical Engineering, Nanjing University of Science and Technology, and the Department of Biology, Texas State University, USA. He is mainly engaged in teaching and research in microbiology and immunology, biopharmaceuticals. He has presided over or participated in more than 10 projects of National 863 Programme, National Natural Science Foundation of China, three projects of Jiangsu Province, Natural Science Foundation of Jiangsu Province, and AQSIQ, etc. He has applied for 15 national invention patents as an inventor, and has been authorised to apply for 8 patents; he has published more than 100 papers, of which more than 80 are SCI-indexed.

1、 Yang Zhao, Minyu Wang, Weihua Chu*Neurotoxicity and intestinal microbiota dysbiosis induced by per- and polyfluoroalkyl substances in crucian carp (Carassius auratus). Journal of Hazardous Materials 2024,478: 135611.

2、 Yang Zhao, Shipo Li, Duncan James Lessing, Weihua Chu*. The attenuating effects of synbiotic containing Cetobacterium somerae and Astragalus polysaccharide against trichlorfon-induced hepatotoxicity in crucian carp (Carassius carassius). Journal of Hazardous Materials 2024, 461: 132621.

3、 Jinqiu Liu, Wei Zhu, Duncan James Lessing, Weihua Chu*. Synthetic microbial consortia for the treatment of Clostridioides difficile infection in mice model. Microbial Biotechnology. 2023; 16(10):1985-2006.

4、 Xin Wen, Zheng Wang, Qi Liu, Duncan James Lessing, Weihua Chu*. Acetobacter pasteurianus BP2201 alleviates alcohol-induced hepatic and neuro-toxicity and modulate gut microbiota in mice. Microbial Biotechnology. 2023; 16(9): 1834-1857.

5、 Yunxia Li, Wei Zhu, Yan Jiang, Duncan James Lessing and Weihua Chu*. Synthetic bacterial consortia transplantation for the treatment of Gardnerella vaginalis-induced bacterial vaginosis in mice. Microbiome. 2023, 11:54 

6、 Minyu Wang, Zheng Wang, Duncan James Lessing, Min Guo, and Weihua Chu*. Fusobacterium nucleatum and its metabolite hydrogen sulfide alter gut microbiota composition and autophagy process and promote colorectal cancer progression. Microbiology spectrum, 2023, e0229223, DOI: 10.1128/spectrum.02292-23.

7、 Wugao Liu, Shuxin Zhou, Wei Wang, De Lin, Weihua Chu*. Characterization of urethritis-associated Neisseria meningitidis isolated from men who have sex with women in China. Journal of Infection, 2022, DOI: 10.1016/j.jinf.2022.01.025.

8、 Xiao-Ying Hou, Pei Zhang, Hong-Zhi Du, Yi-Qiao Gao, Rui-Qi Sun, Si-Yuan Qin, Yuan Tian, Jing Li, Yu-Xin Zhang, Wei-Hua Chu*, Zun-Jian Zhang*, Feng-Guo Xu* Prevotella contributes to individual response of FOLFOX in colon cancer. Clinical and Translational Medicine.  2021,10.1002/ctm2.512.

1. National Natural Science Foundation of China (NNSF) ‘Study on the mechanism of Cordyceps polysaccharides in the treatment of chronic kidney disease based on the pathway of “intestinal flora - SCFAs - GPCR/HDAC - mTOR”.

2. National Natural Science Foundation of China (NSFC) ‘Exploring the mechanism of quenching enzyme-producing Bacillus sphaericus intervening in Aeromonas hydrophila infected crucian carp based on the pathway of “group sensing - intestinal flora - intestinal epithelial cells”.

3. National Natural Science Foundation of China (NSFC) ‘Biological Mechanism and Regulation of Conjugated Linoleic Acid Formation in Ruminants’.

4. National High-Tech Research and Development Programme (863 Programme), ‘Development of high-quality feed as a by-product of genetically engineered collagen producing bacteria’.

5. Jiangsu Provincial Science and Technology Innovation Project: ‘Development and Demonstration of Pond Microbial Remediation Agent Based on High-Throughput Sequencing Analysis of Bacterial Colony Structure’.

6. Natural Science Foundation of Jiangsu Province, ‘Development of Highly Efficient Microecological Preparations Based on Bacterial Community Sensing System’