Fanwenpei

Prof. Wenpei Fan is now a full professor at the Center of Advanced Pharmaceuticals and Biomaterials, State Key Laboratory of Natural Medicines, China Pharmaceutical University. He received his PhD in 2015 from Shanghai Institute of Ceramics, Chinese Academy of Sciences. During 2015-2019, he worked at the National Institutes of Health (USA) as a postdoctoral fellow. Since November of 2019, he has been a full professor at China Pharmaceutical University. His research interest focuses on the design and synthesis of multifunctional theranostic nanomedicines for drug delivery, multimodal imaging, and precision synergistic therapy. He has published over 90 papers in reputed journals with H-index of 61. Many research papers are highlighted and reported in Asian Scientist, Chemistry World and other news media. His research findings have attracted extensive attentions.

1. Burst release of encapsulated annexin A5 in tumours boosts cytotoxic T-cell responses by blocking the phagocytosis of apoptotic cells, Nature Biomedical Engineering 2020, 4(11), 1102-1116.

2. A hybrid semiconducting organosilica-based O₂ nanoeconomizer for on-demand synergistic photothermally boosted radiotherapy, Nature Communications 2021, 12, 523.

3. Bioresponsive nano-antibacterials for H₂S-sensitized hyperthermia and immunomodulation against refractory implant–related infections, Science Advances 2022, 8(14), eabn1701.

4. Immunological nanomaterials to combat cancer metastasis, Chemical Society Reviews 2024, 53(12), 6399-6444.

5. Hybrid Membrane-Camouflaged Biomimetic Immunomodulatory Nanoturrets with Sequential Multidrug Release for Potentiating T Cell-Mediated Anticancer Immunity, Journal of the American Chemical Society 2024, 146(27), 18592-18605.

6. Biomimetic Targeting Nanoadjuvants for Sonodynamic and Chronological Multi-Immunotherapy against Holistic Biofilm-Related Infections, Advanced Materials 2024, 36(11), 2308110.

7. Biodegradable Metal-Organic-Framework-Gated Organosilica for Tumor-Microenvironment-Unlocked Glutathione-Depletion- Enhanced Synergistic Therapy, Advanced Materials 2022, 34(12), 2107560.

8. Enzymatic bionanocatalysts for combating peri-implant biofilm infections by specific heat-amplified chemodynamic therapy and innate immunomodulation, Drug Resistance Updates 2023, 67, 100917.

9. Peroxynitrite-Scavenging Organosilica Nanomedicines for Light-Controllable NO Release and Precision On-Demand Glaucoma Therapy, ACS Nano 2023, 17 (21), 20979-20990.

10. Photoactivated Formation of an Extravascular Dynamic Hydrogel as an Intelligent Blood Flow Regulator to Reprogram the Immunogenic Landscape, Nano Letters 2024, 24(19), 5690-5698.

1. Design of multimodal imaging probes (e.g., MRI、NIR FL、PA、PET, etc.) for accurate early diagnosis of various diseases.

2. Development of new treatment protocols (e.g., gene therapy, immunotherapy, starvation therapy, etc.) for efficient synergistic therapy of various diseases.

3. Design of new advanced pharmaceuticals for precision theranostics of various diseases.

1. Jiangsu Youth Technology Innovation “U35” Nomination Award, 2022

2. Jiangsu Specially-Appointed Professor, 2020