Liuxiaomin

Dr. Xiao-Min Liu is a professor and doctoral supervisor at the School of Life Science and Technology, China Pharmaceutical University, as well as the recipient of Jiangsu Specially Appointed Professor award. He has been working at China Pharmaceutical University since 2020. Dr Liu’s research group focuses on the mechanistic study of RNA modification/ translation in the regulation of stem cell fate and cancer, as well as the development of novel RNA-based technologies and molecular drugs for disease diagnosis and treatment. He has published more than 30 papers in international journals including Nature Chemical Biology, Molecular Cell, Nucleic Acids Research and Cell Reports. 

（1）Wang Y#, Wang S#, Meng Z#, Liu XM*, Mao Y*. Determinant of m6A regional preference by transcriptional dynamics. (2024) Nucleic Acids Research 52(7):3510-3521

（2）Wang F#, Zhang J#, Lin X#, Yang L, Zhou Q, Mi X, Li Q, Wang S, Li D, Liu XM*, Zhou J*. METTL16 promotes translation and lung tumorigenesis by sequestering cytoplasmic eIF4E2. (2023) Cell Reports 42(3):112150

（3）Qin M#, Huang L#, Li M#, Shao T, Zhang J, Jiang X, Shao C, Zhao C, Pan Y, Zhou Q*, Wang Y, Liu XM*, Qiu J*. Immunotoxicity Evaluation of Trihalophenolic Disinfection By-Products in Mouse and Human Mononuclear Macrophage Systems: The Role of RNA Epitranscriptomic Modification in Mammalian Immunity. (2023) Environmental Health Perspectives 131(12):127023

（4）Liu XM#*, Mao Y#, Wang S, Zhou J, Qian SB*. METTL3 modulates chromatin and transcription dynamics during cell fate transition. (2022) Cellular and Molecular Life Sciences 79(11): 559

（5）Liu XM*, Zhou J*. Multifaceted regulation of translation by the epitranscriptomic modification N6-methyladenosine. (2021) Critical Reviews in Biochemistry and Molecular Biology 56(2): 137-148

（6）Liu XM*, Wang S, Gan X, Qian SB, Zhou J*. Fluorescein-based monitoring of RNA N6-methyladenosine at single-nucleotide resolution. (2021) Journal of Molecular Cell Biology 13(4): 325-328

（7）Wang S, Zhang J, Wu X, Lin X, Liu XM*, Zhou J*. Differential roles of YTHDF1 and YTHDF3 in embryonic stem cell-derived cardiomyocyte differentiation. (2021) RNA Biology 18(9): 1354-1363

（8）Liu XM, Zhou J, Mao Y, Ji QQ, Qian SB*. Programmable RNA N6-methyladenosine editing using CRISPR/Cas9 conjugates. (2019) Nature Chemical Biology 15(9): 865-871

（9）Liu XM and Qian SB*. Assembly en route. (2019) Nature Structural & Molecular Biology 26: 89-91

（10）Coots RA#, Liu XM#, Mao Y, Dong L, Zhou J, Wan J, Zhang X, Qian SB*. m6A facilitates eIF4F-independent mRNA translation. (2017) Molecular Cell 68(3): 504-514

（1）Mechanistic study of RNA modification/translation in modulating stem cell fate

（2）Functional study of RNA modification/ translation regulation in lung and colorectal cancer

（3）Development of novel RNA-based technologies and molecular drugs for disease treatment

Jiangsu Specially-Appointed Professor

Young Pioneer Research Award, GNU BK21 program

Chun-Tsung (Hui-Chun Chin & Tsung-Dao Lee) Scholar