Lixuanyi

Dr. Li is a lecturer at China Pharmaceutical University, committed to the research in computer-aided drug design. Dr. Li has earned the Ph.D. in Medicinal Chemistry from the same university. Dr. Li aims to expedite the identification of lead compounds by computer technology.

1. “Discovery of Covalent Lead Compounds Targeting 3CL Protease with a Lateral Interactions Spiking Neural Network” published in the journal of Journal of Chemical Information and Modeling, 2024;

2. “Chemical space exploration based on recurrent neural networks: applications in discovering kinase inhibitors” published in the journal of Journal of Cheminformatics, 2020;

3. “Design, synthesis and biological evaluation of novel 3C-like protease inhibitors as lead compounds against SARS-CoV-2” published in the journal of future medicinal chemistry, 2024;

4.“Palladium-Catalyzed Defluorinative Alkylation of gem-Difluoroalkenes with Cyclopropanols: Stereoselective Synthesis of γ-Fluorinated γ,δ-Unsaturated Ketones” published in the journal of Organic Letters, 2024.

Design and synthesis of selective LOXL2 inhibitors for anti-fibrosis study