Niumiaomiao

1、New materials and technologies for pharmaceutical analysis

2、Discovery of original multi-target drugs and lead compounds

1、Yunjiang Zhou, Yunting Zou, Mei Yang, Shuang Mei, Xiaohao Liu, Huiyun Han, Chang-Dong Zhang, Miao-Miao Niu. Highly Potent, Selective, Biostable, and Cell-Permeable Cyclic D-Peptide for Dual-Targeting Therapy of Lung Cancer. Journal of the American Chemical Society 2022, 144 (16): 7117-7128. (IF=16.383)

2、Kaicheng Tang, Xiaoyou Wang, Miao-Miao Niu, Xinyu Wang, Guanghua Zhou, Jinjin Shi, Yang Yu, Zhangbao Chen, Chong Li*. Augmenting the Precise Targeting of Antimicrobial Peptides (AMPs) and AMP-Based Drug Delivery via Affinity-Filtering Strategy. Advanced Functional Materials 2022, 32 (17): 2111344. (IF=18.808)

3、Lufeng Zheng, Ren Ren, Xiaolian Sun, Yunting Zou, Yiru Shi, Bin Di, Miao-Miao Niu. Discovery of a Dual Tubulin and Poly (ADP-Ribose) Polymerase-1 Inhibitor by Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, and Biological Evaluation. Journal of Medicinal Chemistry 2021, 64 (21): 15702-15715. (IF=8.039)

4、Yunjiang Zhou, Yaxin Chen, Yingying Tan, Rong Hu, Miao-Miao Niu. An NRP1/MDM2-Targeted D-Peptide Supramolecular Nanomedicine for High-Efficacy and Low-Toxic Liver Cancer Therapy. Advanced Healthcare Materials 2021, 10 (9): 2002197. (IF=11.092)

5、Yunjiang Zhou, Yaxin Chen, Xing Huang, Yingying Tan, Rong Hu, Chong Li, Miao-Miao Niu. A Supramolecular Nanomedicine Based on Bendamustine and MDM2-Targeted D-Peptide Inhibitor for Breast Cancer Therapy. Advanced Healthcare Materials 2021, 10 (21): 2100980. (IF=11.092)

6、Liting Cheng, Miao-Miao Niu, Tong Yan, Zhongyi Ma, Kexin Huang, Ling Yang, Xin Zhong, Chong Li. Bioresponsive Micro-to-Nano Albumin-Based Systems for Targeted Drug Delivery against Complex Fungal Infections. Acta Pharmaceutica Sinica B 2021, 11 (10): 3220-3230. (IF=14.903)

7、Da-Song Yang, Yin-He Yang, Yunjiang Zhou, Li-Li Yu, Rui-Han Wang, Bin Di, Miao-Miao Niu. A Redox-Triggered Bispecific Supramolecular Nanomedicine Based on Peptide Self-Assembly for High-Efficacy and Low-Toxic Cancer Therapy. Advanced Functional Materials 2020, 30 (4): 1904969. (IF= 19.924)

8、Fang Yan, Guangmei Liu, Tingting Chen, Xiaochen Fu, Miao-Miao Niu. Structure-Based Virtual Screening and Biological Evaluation of Peptide Inhibitors for Polo-Box Domain. Molecules 2019, 25(1): 107. (IF: 3.267)

9、Yunjiang Zhou, Shi Tang, Tingting Chen, Miao-Miao Niu. Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking and Biological Evaluation for Identification of Potential Poly(ADP-Ribose) Polymerase-1 (PARP-1) Inhibitors. Molecules 2019, 24(23): 4258. (IF: 3.267)

10、Yunjiang Zhou, Bin Di, Miao-Miao Niu. Structure-Based Pharmacophore Design and Virtual Screening for Novel Tubulin Inhibitors with Potential Anticancer Activity. Molecules 2019, 24(17): 3181. (IF: 3.267)