Panyi

Dr. Pan is an associate professor at the School of Life Science and Technology, China Pharmaceutical University. Her main research direction is the mechanisms and treatments of tumor development and progression. She graduated with both a bachelor's and a doctorate from Nanjing University.

1) Tingting Tang^#, Zhaocong Yang, Qinhua Zhu, You Wu, Kun Sun, Murad Alahdal, Yanfeng Zhang, Yun Xing, Yumeng Shen, Tiansong Xia, Tao Xi, Yi Pan*, Liang Jin*. Up-regulation of miR-210 induced by a hypoxic microenvironment promotes breast cancer stem cells metastasis, proliferation, and self-renewal by targeting E-cadherin. FASEB J 2018; 12:6.

2) Tingting Tang^#, Changying Guo, Tiansong Xia, Rui Zhang, Ke Zen, Yi Pan*, Liang Jin*. LncCCAT1 Promotes Breast Cancer Stem Cell Function through Activating WNT/beta-catenin Signaling. Theranostics 2019; 9: 7384-7402.

3) Wanyue Shi^#, Tingting Tang^#, Xinping Li^#, Siwei Deng, Ruiyi Li, Yingshan Wang, Yifei Wang, Tiansong Xia, Yanfeng Zhang, Ke Zen, Liang Jin*,Yi Pan*. Methylation-mediated silencing of miR-133a-3p promotes breast cancer cell migration and stemness via miR-133a-3p/MAML1/DNMT3A positive feedback loop. J Exp Clin Cancer Res 2019; 38: 429. 

4) You Wu^#, Wanyue Shi^#, Tingting Tang^#, Yidong Wang, Xin Yin, Yanlin Chen, Yanfeng Zhang, Yun Xing, Yumeng Shen, Tiansong Xia, Changying Guo, Yi Pan*, Liang Jin*. miR-29a contributes to breast cancer cells epithelial-mesenchymal transition, migration, and invasion via down-regulating histone H4K20 trimethylation through directly targeting SUV420H2. Cell Death Dis 2019; 10: 176.

5) Tingting Tang^#, Qinhua Zhu^#, Xinping Li, Gaole Zhu, Siwei Deng, Yingshan Wang, Lingyu Ni, Xinyuan Chen, Yanfeng Zhang, Tiansong Xia, Ke Zen, Yi Pan*, Liang Jin*. Protease Nexin I is a feedback regulator of EGF/PKC/MAPK/EGR1 signaling in breast cancer cells metastasis and stemness. Cell Death Dis 2019; 10: 649.

6) Xinping Li^#, Siwei Deng^#, Xinyao Pang, Yixiao Song, Shiyu Luo, Liang Jin, Yi Pan*. LncRNA NEAT1 Silenced miR-133b Promotes Migration and Invasion of Breast Cancer Cells. Int J Mol Sci 2019; 20.

7) Manman Li^#, Pandi Wu^#, Zhaocong Yang^#, Siwei Deng, Lingyu Ni, Yanfeng Zhang*, Liang Jin*, Yi Pan*. miR-193a-5p Promotes Pancreatic Cancer Cell Metastasis Through SRSF6-mediated Alternative Splicing of OGDHL and ECM1. Am J Cancer Res 2020; 10: 38-59.

8) Xin Yin ^#, Jingyan Yang ^#, Jintian Chen ^#, Ruiqi Ni, Yanhao Zhou, Hao Song, Liang Jin, Tingting Tang*, Yi Pan*. LncRNA CTD-3252C9.4 modulates pancreatic cancer cell survival and apoptosis through regulating IFI6 transcription. Cancer Cell Int. 2021;16;21(1):433.

9) Xinping Li ^#, Jingyan Yang ^#, Ruiqi Ni, Jintian Chen, Yanhao Zhou, Hao Song, Liang Jin*, Yi Pan*. Hypoxia-induced lncRNA RBM5-AS1 promotes tumorigenesis via activating Wnt/β-catenin signaling in breast cancer. Cell Death Dis 2022;2;13(2):95.

Study on the role of regulatory interactions between breast cancer cells and their microenvironment in the development and progression of breast cancer.