Wangchen

Research Directions:Pharmaceutical analysis, Single cell, Molecular diagnosis

1、Educational Experience

(1) 2018/09 - 2021/06, China Pharmaceutical University, School of Pharmacy, Ph.D.

(2) 2015/09 - 2018/06, China Pharmaceutical University, School of Traditional Chinese Medicine, M.D.

(3) 2011/09 - 2015/06, China Pharmaceutical University, School of Traditional Chinese Medicine, B.S.

2、Working Experience

2021/06 ~ , China Pharmaceutical University, School of Pharmacy, Postdoc.

1. Wang, C.; Wang, J.J.; Xue, X.R.; Shen, Y.Y.; Zou, B.J.; Wang, S.H.; Song, Q.X.; Zhou, G.H. An alternative low-cost strategy for simultaneous sensitive detection of adjacent ESR1 mutations in single circulating tumor cell. J. Anal. Test. 2023, 7(1): 89-100. (IF: NA)

2. Weng J.X.; Sheng N.; Wang R.Y.; Liang S.; Wang C.; Bai X.; Zhou G.H., Zou B.J., Song Q.X. Multiplex Visualized Closed-Tube PCR with Hamming Distance 2 Code for 15 HPV Subtype Typing. Anal. Chem. 2021, 93(13): 5529-5536. (IF: 8.008)

3. Wang C.; Zeng H.J.; Zhang L.N.; Shen Y.Y.; Zou B.J.; Wang S.H.; Song Q.X.; Zhou G.H. Sensitive quantitation of ESR1 mutations in cell-free DNA from breast cancer patients using base-specific invasive reaction assisted qPCR. J. Pharm. Biomed. Anal. 2021, 197: 113959. (IF: 3.209)

4. Li Y.; Liu Y.; Wang C.; Xia W.R.; Zheng J.Y.; Yang J.; Liu B.; Liu J.Q.; Liu L.F. Succinate induces synovial angiogenesis in rheumatoid arthritis through metabolic remodeling and HIF-1α/VEGF axis. Free Radic. Biol. Med. 2018, 126: 1-14. (IF: 6.02)

5. Wang C.; Yin Y.H.; Wei Y.J.; Shi Z.Q.; Liu J.Q.; Liu L.F.; Xin G.Z. Rapid identification of herbal compounds derived metabolites using zebrafish larvae as the biotransformation system. J. Chromatogr. A. 2017, 1515: 100-108. (IF: 3.716)

6. Li Y.; Zheng J.Y.; Liu J.Q.; Yang J.; Liu Y.; Wang C.; Ma X.N.; Liu B.L.; Xin G.Z.; Liu L.F. Succinate/NLRP3 Inflammasome Induces Synovial Fibroblast Activation: Therapeutical Effects of Clematichinenoside AR on Arthritis. Front. Immunol. 2016, 7: 532. (IF: 5.511)

(1) Single cell protein analysis;

(2) Development of enzyme assisted molecular diagnosis methods.