Wuhangyi

1. Educational experience

(1) 2019/09-2022/06, Ph.D., Pharmacy, China Pharmaceutical University.

(2)2016/09-2019/06, Master, Pharmacy, Shenyang Pharmaceutical University/Shanghai Institute of Materia Medica, Chinese Academy of Sciences.

(3) 2011/09-2015/06, Bachelor, Pharmacy, Shenyang Pharmaceutical University.

2. Work experience

(1) From 2022/06 to present, Post-doctor, School of Pharmacy, China Pharmaceutical University.

1.Wu, H.Y.; Yang, P.; Li, A.Q.; Jin, X.; Zhang, Z.H.*; Lv, H.X.* Chlorella sp.-ameliorated undesirable microenvironment promotes diabetic wound healing, Acta Pharm Sin B. 2023;1;410-424. (IF: 14.9)

2.Lu, X.Y.; Wu, H.Y.; Liang, Y.P.; Zhang, Z.H.*; Lv, H.X.* Redox-responsive prodrug for improving oral bioavailability of paclitaxel through bile acid transporter-mediated pathway. Int J Pharm. 2021;600;120496. (IF: 6.5)

3.Zhang, S.#; Song, W.T.#; Wu, H.Y.; Wang, J.; Wang, Y.L.; Zhang, Z.H.*; Lv, H.X.*. Lecithins-Zein nanoparticles for antifungal treatment: Enhancement and prolongation of drug retention in skin with reduced toxicity. Int J Pharm. 2020;590;119894. (IF: 5.9)

4.Liang, P.; Wu, H.Y.; Zhang, Z.H.; Jiang, S.L.*, Lv, H.X.*. Preparation and characterization of parthenolide nanocrystals for enhancing therapeutic effects of sorafenib against advanced hepatocellular carcinoma. Int J Pharm. 2020;583;119375. (IF: 5.9)

5.Wu, H.Y.; Yu, M.R.; Miao, Y.Q.; He, S.F.; Dai, Z.; Song, W.Y.; Liu, Y.; Song, S.; Ahmad, E.; Wang, D.K.*; Gan, Y.* Cholesterol-tuned liposomal membrane rigidity directs tumor penetration and anti-tumor effect. Acta Pharm Sin B. 2019;9;858-870. (IF: 6.0)

(1) We applied Chlorella sp. to treat diabetic ulcers. It has been proved that Chlorella sp. could simultaneously reverse the malignant microenvironments of diabetic wound tissues, resulting in excellent wound healing. The results were published in Acta Pharm Sin B, 2022.

(2) We investigated the effect of cholesterol on liposome membrane rigidity. It has been proved that liposome membrane rigidity decreased with the addition of cholesterol, while moderate rigidity had excellent tumor permeability and anti-tumor effects. The results were published in Acta Pharm Sin B, 2019.