Yanming

I have long been engaged in the establishment and application of drug screening models, particularly in the screening of anti-inflammatory activities of natural products, as well as the study of the regulatory mechanisms of physiological barrier functions (such as the blood-testis barrier and renal filtration barrier). In recent years, I have conducted screenings for anti-inflammatory active components in natural products such as Tripterygium wilfordii, Dendrobium officinale, Ainsliaea fragrans Champ., and Baeckea frutescens L., and published 45 SCI-indexed research papers on their therapeutic applications for conditions like diabetic nephropathy, gout, rheumatoid arthritis, and primary dysmenorrhea. I have also been granted 14 patents in China. Collaborating with Jiangsu Province Hospital of Traditional Chinese Medicine, I have been involved in the secondary development of traditional Chinese medicine formulas for controlling proteinuria in diabetic nephropathy and researching the related molecular regulatory mechanisms.

1.Liang Wu#, Ying Yang#, Min Lin, Haiqing Wang, Luqian Li, Haixia Wu, Xue Wang, Ming Yan*. Unraveling the anti-primary dysmenorrhea mechanism of Ainsliaea fragrans Champ. extract by the integrative approach of network pharmacology and experimental verification. Phytomedicine. 2024 Jan, 123:155213. IF: 7.9 Q1

2.Decai Fan#, Zi Ying#, Ying Yang, Qi Qian, Yuanyuan Li, Panjun Wang, Xiaofei An*, Ming Yan*. Deciphering the anti-renal fibrosis mechanism of triptolide in diabetic nephropathy by the integrative approach of network pharmacology and experimental verification. J Ethnopharmacol. 2023 Jun 11;116774  IF:5.4 Q2

The steroidogenesis regulation study of triptolide on rat Leydig cells and mouse Leydig tumor cells, the National Natural Science Foundation of China (No. 81102876)

1. First prize of scientific and technological progress of Jiangsu Provincial Government，2006

2. Second prize of scientific and technological progress by Ministry of Education, 2014

Encyclopedia of Reproduction (Second Edition), Academic Press, 2018, ISBN: 9780128118993, is responsible for the chapter on Testis Toxicants. (Editor-in-Chief: Michael Skinner)