Zhangpei

1、Educational Experience

2012.09 – 2017.06PhD in Pharmaceutical Analysis, Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education), China Pharmaceutical University, Nanjing, China

2007.09 – 2011.06BSc in Pharmacy, School of Pharmacy, Soochow University, Suzhou, China

2、Working Experience

2022.07 – nowAssociate Professor, School of Pharmacy, China Pharmaceutical University, Nanjing, China

2021.01 – 2022.06 Lecture, School of Pharmacy, China Pharmaceutical University, Nanjing, China

2019.08 – 2019.10 Visiting Scholar, Karolinska Institutet, Stockholm, Sweden

2017.11 – 2020.11Postdoctoral Researcher, Overseas Laboratory of Karolinska Institutet at Gunma University, Maebashi, Japan

1. Chen, J.;(#) Zhang, P.;(#) Qin, S.; Tan, B.; Li, S.; Tang, S.; Liao, C.; Zhang, Y.; Zhang, Z.; Xu, F., Stepwise solid phase extraction integrated with chemical derivatization for all-in-one injection LC-MS/MS analysis of metabolome and lipidome. Anal Chim Acta 2023, 1241, 340807. (IF: 6.558)

2. Li, W.;(#) Zhang, P.;(#) Hou, X.; Tang, T.; Li, S.; Sun, R.; Zhang, Z.;(*) Xu, F.,(*) Twins labeling derivatization-based LC-MS/MS strategy for absolute quantification of paired prototypes and modified metabolites. Anal Chim Acta 2022, 1193, 339399. (IF: 6.558)

3. Liao, C.; Wang, D.; Qin, S.; Zhang, Y.; Chen, J.; Xu, R.; Xu, F.;(*) Zhang, P.,(*) Inflammatory-Dependent Bidirectional Effect of Bile Acids on NLRP3 Inflammasome and Its Role in Ameliorating CPT-11-Induced Colitis. Front Pharmacol 2022, 13, 677738. (IF: 5.988)

4. Lv, B.; Xu, R.; Xing, X.; Liao, C.; Zhang, Z.; Zhang, P.;(*) Xu, F.,(*) Discovery of Synergistic Drug Combinations for Colorectal Cancer Driven by Tumor Barcode Derived from Metabolomics Big Data. Metabolites 2022, 12 (6). (IF: 5.581)

5. Zhang, Y.; Wang, D.; Lv, B.; Hou, X.; Liu, Q.; Liao, C.; Xu, R.; Zhang, Y.; Xu, F.;(*) Zhang, P.,(*) Oleic Acid and Insulin as Key Characteristics of T2D Promote Colorectal Cancer Deterioration in Xenograft Mice Revealed by Functional Metabolomics. Front Oncol 2021, 11, 685059. (IF: 6.244)

6. Hou, X.;(#) Zhang, P.;(#) Du, H.; Gao, Y.; Sun, R.; Qin, S.; Tian, Y.; Li, J.; Zhang, Y.; Chu, W.; Zhang, Z.;(*) Xu, F.,(*) Prevotella contributes to individual response of FOLFOX in colon cancer. Clin Transl Med 2021, 11 (9), e512. (IF: 11.492)

7. Tang, T.;(#) Zhang, P.;(#) Li, S.; Xu, D.; Li, W.; Tian, Y.; Jiao, Y.; Zhang, Z.;(*) Xu, F.,(*) Absolute Quantification of Acylcarnitines Using Integrated Tmt-PP Derivatization-Based LC-MS/MS and Quantitative Analysis of Multi-Components by a Single Marker Strategy. Anal Chem 2021, 93 (38), 12973-12980. (IF: 6.986)

8. Tan, B.; Chen, J.; Qin, S.; Liao, C.; Zhang, Y.; Wang, D.; Li, S.; Zhang, Z.; Zhang, P.;(*) Xu, F.,(*) Tryptophan Pathway-Targeted Metabolomics Study on the Mechanism and Intervention of Cisplatin-Induced Acute Kidney Injury in Rats. Chem Res Toxicol 2021, 34 (7), 1759-1768. (IF: 3.739)

9. Zhang, P.; Carlsten, C.; Chaleckis, R.; Hanhineva, K.; Huang, M.; Isobe, T.; Koistinen, V. M.; Meister, I.; Papazian, S.; Sdougkou, K.; Xie, H.; Martin, J. W.; Rappaport, S. M.; Tsugawa, H.; Walker, D. I.; Woodruff, T. J.; Wright, R. O.; Wheelock, C. E.,(*) Defining the Scope of Exposome Studies and Research Needs from a Multidisciplinary Perspective. Environ Sci Tech Lett 2021, 8 (10), 839-852. (IF: 7.653)

10. Zhang, P.; Li, W.; Chen, J.; Li, R.; Zhang, Z.; Huang, Y.;(*) Xu, F.,(*) Branched-Chain Amino Acids as Predictors for Individual Differences of Cisplatin Nephrotoxicity in Rats: A Pharmacometabonomics Study. J Proteome Res 2017, 16 (4), 1753-1762. (IF: 3.950)

(1)National Natural Science Foundation of China, Youth Program, Characterizing the origin and metabolism of 1-methyladenosine in cisplatin resistant non-small cell lung cancer, 2022.01 - 2024.12, No. 82104117, Principal Investigator, In progress.

(2）Jiangsu Natural Science Foundation, Youth Program, Study on the metabolism of 1-methyladenosine and its correlation with cisplatin-induced drug resistance in non-small cell lung cancer, 2021.07 - 2024.06, No. BK20210427, Principal Investigator, In progress.

(3)Japan Society for the Promotion of Science (JSPS), Integrative Metabolomics and Exposomics Study of Severe Asthma in Adults, 2018.4 - 2020.3, No. 18H06121, 19K21239, Principal Investigator, Completed.