Release date:2016-05-17  Release:




Associate Professor of Medicinal Chemistry

School of Pharmacy

Phone: 86-25-83271445


Research Summary

Dr. LIN’s research focuses on the lead compound discovery and development, by the means of drug design, synthesis, molecular and structural biology. Specifically, based on the receptor structures provided by NMR or X ray, innovative compounds are designed  by computer-aided drug design. After synthesis, the biological activities and  interactions between drugs and receptors are examined by molecular and structural biology methods. Primarily driven bytrial and error,  novel drugs are patented. Recently Dr. LIN eyes on the diseases caused by multi-drug resistant.


2012       Ph.D., Medicinal Chemistry, China Pharmaceutical University

2003       M.S.,  Medicinal ChemistryChina Pharmaceutical University

Academic Experience

2005-      Associate Professor of Medicinal Chemistry, China Pharmaceutical University


Zhang, Z.; Wu, G.; Wang, C.; Jin, X.; Li, D.; Lin, K., Features of reversible P2Y12 receptor antagonists based on piperazinyl-glutamate-pyridines. Med. Chem. Res. 2016,25 (6), 1204-1215.

Wu, G.; Zhang, Z.; Chen, H.; Lin, K., De novo design of caseinolytic protein proteases inhibitors based on pharmacophore and 2D molecular fingerprints. Bioorg. Med. Chem. Lett. 2015,25 (11), 2345-52.

Lin, K.; Yu, Z.; Yu, Y.; Liao, X.; Huang, P.; Guo, C.; Lin, D., Distinct effects of Cu2+-binding on oligomerization of human and rabbit prion proteins. Acta biochimica et biophysica Sinica 2015,47 (10), 842-50.

LIN, K.-J.; HUANG, Z.-G.; Li, T.; WANG, N.-X.; CHENG, Y.; SHEN, L.-L.; WANG, Y.-T.; LI, H.; YE, B., The structural characteristics of cannabinoid type 1 receptor antagonists. Chem. J. Chinese Universities 2013,34 (5), 1240-1245.

HUANG, Z.-G.; LIN, K.-J.; YIN, H.-P.; YE, B.-P.; WENG, X.-B.; YOU, Q.-D., Virtual Screening and Antibacterial Activity of Novel Inhibitors Targeting the DNA Gyrase with New Mechanism. Chem. J. Chinese Universities 2013,34 (8), 1887-1893.

Huang, Z.; Lin, K.; You, Q., De novo design of novel DNA-gyrase inhibitors based on 2D molecular fingerprints. Bioorg. Med. Chem. Lett. 2013,23 (14), 4166-4171.

LIN, K.-J.; ZHU, D.-J.; LENG, Y.-G.; YOU, Q.-D., Structural Characterization of Human Parathyroid Hormone 1 Receptor. Acta Physico-Chimica Sinica 2012,28 (7), 1783-1789.

Lin, K.; Len, Y.; Feng, J.; Gao, H.; You, Q.; Lin, D., Structure of a novel PTH-related peptide hPTH' and its interaction with the PTH receptor. J. Pept. Sci. 2012,18 (6), 413-417.

Huang, L.; Huang, Z.; Bai, Z.; Xie, R.; Sun, L.; Lin, K., Development and strategies of VEGFR-2/KDR inhibitors. Future Med Chem 2012,4 (14), 1839-52.