Release date:2016-05-18  Release:


Professor of Chinese Medicines Analysis

Director of the Department of Chinese Medicines Analysis

School of Traditional Chinese Pharmacy

Phone: 86-25-86185136


Research Summary

Professor Liu’s research focuses on active materials and quality evaluation of traditional Chinese medicines (TCMs). Recently, her work contains three main aspects: 1. Investigate the effects of triterpene saponins from Chinese herbs on gut microflora balance to reveal their mechanism of anti-inflammatory. 2. Use metabonomics method and technology to find the main biomarkers of TCMs in the treatment of autoimmune diseases, such as rheumatoid arthritis and ulcerative colitis. 3. Explore new methods for the rapid discrimination of Chinese medicinal materials with multiple botanical origins based on metabolite profiling and chemometrics analysis.


1999 Ph.D., Pharmacognosy,ChinaPharmaceutical University

1992 B.S., Chinese materia medica, China Pharmaceutical University

Academic Experience

2010-present, Professor, Ph.D. supervisor,Department of Chinese Medicines Analysis, China Pharmaceutical University

2002-2010, Associate professor, Department of Chinese Medicines Analysis, China Pharmaceutical University

Jun. 2006- Dec. 2006, Visitingscholar, School of Medicine, University of California, Irvine

2002- 2004, Post-doctorate, Department of Biochemistry and National key Laboratory of Pharmaceutical Biotechnology, Nanjing University

1999-2002, Lecture, Department of Chinese Medicines Analysis, China Pharmaceutical University

Jan. 1999-Jul. 1999, Visitingscholar, Department of Biochemistry, the Chinese University of Hongkong

1992- 1994, Assistant engineer, Drug research institute of Jiangxi Chinese medicines factory

Awards and Honors

2004“Qinglan Project”excellent young colleges teacher, Jiangsu Provincial Department of Education



1. Liu Li-Fang, Analysis Science of Chinese Medicines, Beijing, China Medical Science Press, Aug, 2015

2. Editor of Pharmacopoeia of the People`s Republic of China(English Edition), China Medical Science Press, 2015

3. LiPing, Liu Li-Fang, Bi Zhi-Ming, The identification of commonly used Traditional Chinese Medicines by HPLC and GC methods, Beijing, Chemical Industry Press, Mar, 2005

Papers and Articles

1. Xiao-Lin Zhang#, Li-Fang Liu#, Ling-Ying Zhu, Ying-Jia Bai, Qian Mao, Song-Lin Li*, Shi-Lin Chen, Hong-Xi Xu*, A HPLC fingerprinting and UPLC-QTOF mass spectrometry chemical  profiling approach to rapidly find characteristic chemical markers for quality evaluation of dispensing granules, a case study on Chuanxiong Rhizoma, Journal of Pharmaceutical and Biomedical Analysis, 2014, 88, 391-400 (IF=2.979)

2. Gui-Zhong Xin#, Bin Hu#, Zi-Qi Shi, Jia-Yi Zheng, Li Wang, Wen-Qi Chang, Ping Li, Zhong-Ping Yao, Li-Fang Liu*, A direct ionization mass spectrometry-based approach for differentiation of medicinal Ephedra species. Journal of Pharmaceutical and Biomedical Analysis, 2016, 117: 492-498 (IF=2.979)

3. Li Wang, Zhong-Ping Yao, Ping Li, Si-Bao Chen, Pui-Kin So, Zi-Qi Shi, Bin Hu, Li-Fang Liu*, Gui-Zhong Xin*. Global detection and semi-quantification of Fritillaria alkaloids in Fritillariae Ussuriensis Bulbus by a non-targeted multiple reaction monitoring approach. Journal of separation science, 2016, 39(2): 287-295 (IF=2.737)

4. Su-Min Duan#, Jun Xu#, Ying-Jia Bai, Yan Ding, Ming Kong, Huan-Huan Liu, Xiu-Yang Li, Qing-Shan Zhang, Hu-Biao Chen, Li-Fang Liu*, Song-Lin Li*, Sulfur dioxide residue in sulfur-fumigated edible herbs: The fewer, the safer? Food Chemistry, 2016, 192, 119–124 (IF=3.391)

5. Lin-Xiu Guo, Rui Li, Ke Liu, Jie Yang, Hui-Jun Li, Song-Lin Li, Jian-Qun Liu, Li-Fang Liu*, Gui-Zhong Xin*, Structural characterization and discrimination of Chinese medicinal materials with multiple botanical origins based on metabolite profiling and chemometrics analysis: Clematidis Radix et Rhizoma as a case study. Journal of Chromatography A, 11425, 2015, 129–140 (IF=4.169)

6.Ying-Jia Bai#, Jin-Di Xu#, Ming Kong, Qiong Gao, Li-Fang Liu*, Song-Lin Li*, Discovery of characteristic chemical markers for inspecting sulfur-fumigated Radix Angelicae Sinensis by UPLC–Q/TOF mass spectrometry based metabolomics and chemical profiling approach, Food Research International, 2015, 76: 387–394 (IF=2.818)

7.Ying-Jia Bai#, Ming Kong#, Jin-Di Xu, Xiao-Lin Zhang, Shan-Shan Zhou, Xiao-Ning Wang, Li-Fang Liu*,Song-Lin Li*, Effect of different drying methods on the quality of Angelicae Sinensis Radix evaluated through simultaneously determining four types of major bioactive components by high performance liquid chromatography photodiode array detector and ultra-high performance liquid chromatography quadrupole time-of-flight mass spectrometry, Journal of Pharmaceutical and Biomedical Analysis, 2014, 94, 77-83 (IF=2.979)

8. Yang Zhou, Yue Guan, Ji Shi, Xiao-Lin Zhang, Lan Yao, Li-Fang Liu*, Development and validation of chromatographic method for determining Clematichinenoside AR and related impurities, Chemistry Central Journal, 2012, 6, 150-160 (IF=2.187)