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1. Ren XQ, Huang X, Xing SY, Long Y, Yuan DH, Hong H, Tang SS*. Neuroprotective effects of novel compound FMDB on cognition, neurogenesis and apoptosis in APP/PS1 transgenic mouse model of Alzheimer's disease. Neurochem Int. 2023, 165: 105510. (IF: 4.297) 2. Chen F, Fang S, Du Y, Ghosh A, Reed MN, Long Y, Suppiramaniam V, Tang S*, Hong H*. CRISPR/Cas9-mediated CysLT1R deletion reverses synaptic failure, amyloidosis and cognitive impairment in APP/PS1 mice. Aging (Albany NY). 2021, 13(5):6634-6661. (IF: 5.955) 3. Chen F, Ghosh A, Lin J, Zhang C, Pan Y, Thakur A, Singh K, Hong H*, Tang S*. 5-lipoxygenase pathway and its downstream cysteinyl leukotrienes as potential therapeutic targets for Alzheimer’s disease. Brain Behav Immun. 2020, 88: 844-855. (IF:7.217) 4. Tang SS*#, Ren Y#, Ren XQ, Cao JR, Hong H, Ji H, Hu QH*. ERα and/or ERβ activation ameliorates cognitive impairment, neurogenesis and apoptosis in type 2 diabetes mellitus mice. Exp Neuro. 2019, 311: 33-43. (IF: 5.33) 5. Chen F#, Yu XB#, Meng GL, Mei ZL, Du YF, Sun HB, Reed MN, Kong LY, Suppiramaniam V, Hong H*, Tang SS*. Hippocampal Genetic Knockdown of PPARδ Causes Depression-Like Behaviors and Neurogenesis Suppression. Int J Neuropsychopharmacol. 2019, 22 (6), 372-382. (IF:5.176) 6. Wu X, Lv YG, Du YF, Hu M, Reed MN, Long Y, Suppiramaniam V, Hong H*, Tang SS*. Inhibitory effect of INT-777 on lipopolysaccharide-induced cognitive impairment, neuroinflammation, apoptosis, and synaptic dysfunction in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2019, 88:360-374. (IF: 5.067) 7. Wu X, Lv YG, Du YF, Chen F, Reed MN, Hu M, Suppiramaniam V, Tang SS*, Hong H*. Neuroprotective effects of INT-777 against Aβ1-42-induced cognitive impairment, neuroinflammation, apoptosis, and synaptic dysfunction in mice. Brain Behav Immun. 2018, 73: 533-545. (IF: 6.17) 8. Tang SS*, Ren Y, Xu LJ, Cao JR, Hong H, Ji H, Hu QH*. Activation of ERα and/or ERβ ameliorates cognitive impairment and apoptosis in streptozotocin-induced diabetic mice. Horm Behav. 2018, 105: 95-103. (IF:4.418) 9. Wang H, Chen F, Du YF, Long Y, Reed MN, Hu M, Suppiramaniam V, Hong H*, Tang SS*. Targeted inhibition of RAGE reduces amyloid-β influx across the blood-brain barrier and improves cognitive deficits in db/db mice. Neuropharmacology. 2018, 131:143-153. (IF:4.367) Li DD, Xie H, Du YF, Long Y, Reed MN, Hu M, Suppiramaniam V, Hong H*, Tang SS*. Antidepressant-like effect of zileuton is accompanied by hippocampal neuroinflammation reduction and CREB/BDNF upregulation in lipopolysaccharide-challenged mice. J Affect Disord. 2017, 227:672-680. (IF:3.786) 1. Ren XQ, Huang X, Xing SY, Long Y, Yuan DH, Hong H, Tang SS*. Neuroprotective effects of novel compound FMDB on cognition, neurogenesis and apoptosis in APP/PS1 transgenic mouse model of Alzheimer's disease. Neurochem Int. 2023, 165: 105510. (IF: 4.297) 2. Chen F, Fang S, Du Y, Ghosh A, Reed MN, Long Y, Suppiramaniam V, Tang S*, Hong H*. CRISPR/Cas9-mediated CysLT1R deletion reverses synaptic failure, amyloidosis and cognitive impairment in APP/PS1 mice. Aging (Albany NY). 2021, 13(5):6634-6661. (IF: 5.955) 3. Chen F, Ghosh A, Lin J, Zhang C, Pan Y, Thakur A, Singh K, Hong H*, Tang S*. 5-lipoxygenase pathway and its downstream cysteinyl leukotrienes as potential therapeutic targets for Alzheimer’s disease. Brain Behav Immun. 2020, 88: 844-855. (IF:7.217) 4. Tang SS*#, Ren Y#, Ren XQ, Cao JR, Hong H, Ji H, Hu QH*. ERα and/or ERβ activation ameliorates cognitive impairment, neurogenesis and apoptosis in type 2 diabetes mellitus mice. Exp Neuro. 2019, 311: 33-43. (IF: 5.33) 5. Chen F#, Yu XB#, Meng GL, Mei ZL, Du YF, Sun HB, Reed MN, Kong LY, Suppiramaniam V, Hong H*, Tang SS*. Hippocampal Genetic Knockdown of PPARδ Causes Depression-Like Behaviors and Neurogenesis Suppression. Int J Neuropsychopharmacol. 2019, 22 (6), 372-382. (IF:5.176) 6. Wu X, Lv YG, Du YF, Hu M, Reed MN, Long Y, Suppiramaniam V, Hong H*, Tang SS*. Inhibitory effect of INT-777 on lipopolysaccharide-induced cognitive impairment, neuroinflammation, apoptosis, and synaptic dysfunction in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2019, 88:360-374. (IF: 5.067) 7. Wu X, Lv YG, Du YF, Chen F, Reed MN, Hu M, Suppiramaniam V, Tang SS*, Hong H*. Neuroprotective effects of INT-777 against Aβ1-42-induced cognitive impairment, neuroinflammation, apoptosis, and synaptic dysfunction in mice. Brain Behav Immun. 2018, 73: 533-545. (IF: 6.17) 8. Tang SS*, Ren Y, Xu LJ, Cao JR, Hong H, Ji H, Hu QH*. Activation of ERα and/or ERβ ameliorates cognitive impairment and apoptosis in streptozotocin-induced diabetic mice. Horm Behav. 2018, 105: 95-103. (IF:4.418) 9. Wang H, Chen F, Du YF, Long Y, Reed MN, Hu M, Suppiramaniam V, Hong H*, Tang SS*. Targeted inhibition of RAGE reduces amyloid-β influx across the blood-brain barrier and improves cognitive deficits in db/db mice. Neuropharmacology. 2018, 131:143-153. (IF:4.367) Li DD, Xie H, Du YF, Long Y, Reed MN, Hu M, Suppiramaniam V, Hong H*, Tang SS*. Antidepressant-like effect of zileuton is accompanied by hippocampal neuroinflammation reduction and CREB/BDNF upregulation in lipopolysaccharide-challenged mice. J Affect Disord. 2017, 227:672-680. (IF:3.786) (1) National Natural Science Foundation of China, No.82071202, 2021-01-01 to 2024-12-31 (2) National Natural Science Foundation of China, No.81603113, 2017-01-01 to 2019-12-31 (3) Department of Science and Technology of Jiangsu Province, Natural Science Foundation of Jiangsu Province, No.BK20150705, 2015-07-01 to 2018-06-30 |

