Wujianbing

Dr. Wu holds a PhD in Medicinal Chemistry from China Pharmaceutical University. He currently serves as an associate professor and graduate supervisor. Dr. Wu has made significant advancements in the field of nitric oxide-related drugs. His research interests have recently expanded to encompass the investigation of protein post-translational modification regulators and protein-drug conjugates (PDCs).

(1)Development of Integrated Bioorthogonal Self-Catalyzed NO Donor/Platinum(IV) Prodrugs for Synergistical Intervention against Triple-Negative Breast Cancer. J. Med. Chem. 2023, 67, 479-491.

(2)One Stone Two Birds: Redox-Sensitive Colocalized Delivery of Cisplatin and Nitric Oxide through Cascade Reactions. JACS Au 2022, 2, 2339-2351.

(3)Novel Nitric Oxide Donor-Azole Conjugation Strategy for Efficient Treatment of Cryptococcus neoformans Infections. J. Med. Chem. 2023, 66, 14221-14240.

(4)1,3-Substituted β-Carboline Derivatives as Potent Chemotherapy for the Treatment of Cystic Echinococcosis. J. Med. Chem. 2023, 66, 16680-16693.

(5)Design, Synthesis, and Biological Evaluation of Organic Nitrite (NO2-) Donors as Potential Anticerebral Ischemia Agents. J. Med. Chem. 2021, 64, 10919-10933.

(1)Molecular construction and mechanism exploration of novel nitric oxide donating drugs.

(2)Design and synthesis of novel protein-drug conjugates and their biological evaluation.

China International College Students’ Innovation Competitin 2023, Gold Prize (Advisor 4/5)